Evidence map›Paper›PMID 40458680›Full record

ArticleThe journal of allergy and clinical immunology. Global2025

A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis.

Sonia Iqbal, Joseph A Baxter, Karla E Adams

Abstract readCase Reports
In one paragraph

Article in The journal of allergy and clinical immunology. Global, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sonia IqbalDepartment of Internal Medicine, Malcolm Grow Medical Center, Joint Base Andrews, Md.
Joseph A BaxterDepartment of Allergy and Immunology, 56th Medical Group, Luke Air Force Base, Ariz.
Karla E AdamsDepartment of Allergy and Immunology, Wilford Hall Ambulatory Surgical Center, Lackland Air Force Base, Tex.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders.

Indexed as

elevated tryptase leveleosinophilic granulomatosis with polyangiitisHereditary alpha tryptasemiahypereosinophiliamepolizumab

Identifiers

PMID40458680
PMCPMC12127639

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.