ArticleFrontiers in medicine2025
Enhanced hemodynamic stability and patient satisfaction with ciprofol-remifentanil versus propofol-remifentanil for sedation in shorter-duration fiberoptic bronchoscopy: a prospective, randomized, double-blind study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Ciprofol versus propofol and the risk of hemodynamic adverse events: a meta-analysis with trial sequential analysis of randomized controlled trials.BMC anesthesiology · 2026Pooled it
- Comparison of anesthetic effects of different sedative drugs combined with remifentanil for general anesthesia in bronchoscopy: a randomized controlled trial.BMC anesthesiology · 2026Trial
- Effects of Ciprofol Combined with Varying Doses of Alfentanil on Anesthetic Efficacy and Safety in Pediatric Bronchoscopy: A Randomized Controlled Trial.Drug design, development and therapy · 2026Trial
- Post-Intubation Hypotension After Titrated Induction with Ciprofol versus Propofol in Older Adults Undergoing Non-Cardiac Surgery: A Randomized Controlled Trial.Clinical interventions in aging · 2026Trial
- Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia.Children (Basel, Switzerland) · 2026Review
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aimed to compare the efficacy and safety of ciprofol-remifentanil versus propofol-remifentanil in patients undergoing fiberoptic bronchoscopy (FOB). Methods: In this prospective, randomized, double-blind, non-inferiority trial, 209 patients undergoing FOB were enrolled and equally divided into two groups ( Results: The successful completion rate of FOB was 92.45% (98 of 106) in the ciprofol-remifentanil group and 90.57% (96 of 106) in the propofol-remifentanil group ( Conclusion: Ciprofol-remifentanil was non-inferior to propofol-remifentanil in terms of sedation during fiberoptic bronchoscopy;. Furthermore, ciprofol-remifentanil was associated with greater hemodynamic stability, reduced pain on injection, and higher satisfaction scores, suggesting that it may be a preferable alternative to propofol-remifentanil for FOB procedures. Clinical trial registration: https://www.chictr.org.cn/, ChiCTR2400081603.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.