Evidence map›Paper›PMID 40458473›Full record

ArticlePreventive medicine reports2025

Patient preferences for stroke prevention treatments in atrial fibrillation in Asia: A discrete choice experiment.

Rosa Wang, Hui Lu, Gabriela Fernandez, Nicolas Krucien, Dong Huang, Hiroshi Higashiyama, Juan Du, Xin Ye, Tommi Tervonen, Matthew Quaife

Abstract read
In one paragraph

Article in Preventive medicine reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. A double paradox: end-stage renal disease-high thromboembolic and bleeding risk management using a device with risks of thromboembolism and bleeding.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rosa WangDaiichi Sankyo, Inc., Basking Ridge, NJ, United States.
Hui LuEvidera, London, United Kingdom.
Gabriela FernandezEvidera, Bethesda, MD, United States.
Nicolas KrucienEvidera, London, United Kingdom.
Dong HuangHeart Center, Shanghai Jiaotong University Affiliated Sixth People's Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Hiroshi HigashiyamaDaiichi Sankyo Holdings Co., Ltd, Shanghai, China.
Juan DuDaiichi Sankyo Holdings Co., Ltd, Shanghai, China.
Xin YeDaiichi Sankyo, Inc., Basking Ridge, NJ, United States.
Tommi TervonenKielo Research, Zug, Switzerland.
Matthew QuaifeEvidera, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Stroke prevention in patients with atrial fibrillation should be adapted to patient needs and preferences. This study quantifies patient preferences for key characteristics of atrial fibrillation stroke prevention treatments in China, Taiwan, and South Korea. Methods: A discrete choice experiment (DCE) survey was developed based on a targeted literature review and discussions with clinical and methodological experts. The DCE included six attributes: risks of death, severe disabilities, mild or moderate disabilities, non-disabling events; intake with food; and dosing frequency. DCE data were analyzed using mixed multinomial logit models. Results: In January to March 2023, 307 participants completed the DCE in China ( Conclusion: Patients with atrial fibrillation were willing to accept an increased risk of non-disabling events in exchange for a reduced risk of death but had diverse preferences for treatment administration characteristics. These findings can inform patient-centered treatment strategies that consider the relative importance of treatment attributes in clinical decision-making.

Indexed as

Atrial fibrillationDirect oral anticoagulantDiscrete choice experimentPatient preferencesStroke preventionTreatment attributes

Identifiers

PMID40458473
PMCPMC12127864

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.