ArticleFrontiers in neurology2025
Cochlear signal intensity changes in vestibular schwannoma: a balanced fast field-echo MRI study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- [Audiological findings and analysis in 93 cases of unilateral vestibular schwannoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Article
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9 authors.
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Abstract
Introduction: Vestibular schwannoma (VS) is a benign tumor associated with cochlear degeneration and sensorineural hearing loss (SNHL). This study aimed to evaluate cochlear signal intensity in VS patients using balanced fast field-echo (bFFE) magnetic resonance imaging (MRI) and to explore its relationship with tumor size, hearing loss, and postoperative changes. Methods: A retrospective analysis was conducted on 165 VS patients and 30 SNHL control patients who underwent bFFE MRI at Kobe University Hospital from 2008 to 2019. Cochlear signal intensity was measured bilaterally using regions of interest (ROIs), and signal intensity ratios (affected/normal) were calculated. Statistical analyses included linear regression and ANOVA to evaluate correlations with hearing levels, tumor size, and postoperative changes. Results: VS patients exhibited significantly lower cochlear signal intensity ratios on the affected side compared to controls (75.3% vs. 100%, Discussion: Decreased cochlear signal intensity in VS patients may indicate protein concentration changes due to tumor secretions. bFFE MRI effectively captures these changes, providing insights into cochlear physiology and tumor impact. Conclusion: bFFE MRI is a reliable tool for assessing cochlear signal intensity in VS patients, offering potential for improved tumor evaluation, surgical planning, and postoperative monitoring.
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