ReviewRSC advances2025
A green marriage: the union of theophylline's catalytic activity and healing potential.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent studies, theophylline has been shown to be a green, effective, and biodegradable catalyst suitable for various multicomponent processes. This review explores theophylline's biological synthesis, catabolism, and advanced extraction methods, demonstrating its versatility. Theophylline is utilized to synthesize metal complexes through innovative methods, including the preparation of imidazolium salts and their conversion into N-heterocyclic carbene (NHC) ligands. The therapeutic application of theophylline in the pharmaceutical and medical domains is enhanced by these complexes, which exhibit encouraging potential as antimicrobial and anticancer agents. It exhibits a high yield and efficiency in organic reactions, particularly in acylation, methylation, and nucleophilic substitution reactions, making it a good fit for industrial processes. The review also discusses potential neurological side effects of theophylline and offers prevention and therapy options. It is recommended for future studies to in-depth elucidate theophylline's properties, effects, and uses for improving industrial operations and treating medical conditions. In this thorough analysis, theophylline's adaptability and potential are highlighted, paving the way for more research and development of its wide range of applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.