Evidence map›Paper›PMID 40458422›Full record

ArticleBrain & spine2025

Optimizing microvascular decompression for trigeminal Neuralgia: Addressing vertebrobasilar ectasia challenges - A technical note.

Pavlina Lenga, Carola Wieckhusen, Mohammad Mehdi Hajiabadi, Andreas Unterberg, Sandro M Krieg, Rezvan Ahmadi

Abstract read
In one paragraph

Article in Brain & spine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pavlina LengaDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Carola WieckhusenDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Mohammad Mehdi HajiabadiDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Andreas UnterbergDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Sandro M KriegDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
Rezvan AhmadiDepartment of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Trigeminal neuralgia (TN) can be due vertebrobasilar ectasia (VBE), where elongated, tortuous arteries compress the trigeminal nerve, making surgical management challenging. Research question: Does a refined microvascular decompression (MVD) technique using a "Teflon cloud" interposition offer sustained symptom relief and medication discontinuation in VBE-induced TN? Materials and methods: Three patients with VBE-induced TN were treated between 2017 and 2024. Diagnosis was confirmed by MRI/MRA. MVD with a "Teflon cloud" was performed to cushion the nerve without extensive arterial manipulation. Postoperative outcomes were tracked over an 8-month follow-up. Results: All patients showed immediate, complete relief of TN symptoms, with no recurrences. They discontinued TN-related medications within three months, and no significant complications occurred. Discussion and conclusion: These findings suggest that interposition-based MVD using a Teflon cloud effectively addresses TN in the context of VBE by providing stable nerve decompression and minimizing vascular manipulation. A refined MVD with a "Teflon cloud" interposition provides safe, sustained relief for VBE-induced TN, warranting further investigation in larger patient cohorts.

Indexed as

Microvascular decompressionNeurovascular compressionTrigeminal neuralgiaVertebrobasilar ectasia

Identifiers

PMID40458422
PMCPMC12127552

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.