Evidence map›Paper›PMID 40458368›Full record

ArticleCureus2025

Concurrent Breast Cancer and Vulvar Leiomyoma in a 62-Year-Old Patient: A Comprehensive Case Report.

Cristina Bacalam, Daniel Sur, Ovidiu Bochis, Rares Buiga

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cristina BacalamDepartment of Medical Oncology, The Oncology Institute "Prof. Dr. Ion Chiricuţă" Cluj-Napoca, Cluj-Napoca, ROU.
Daniel SurDepartment of Medical Oncology, The Oncology Institute "Prof. Dr. Ion Chiricuţă" Cluj-Napoca, Cluj-Napoca, ROU.
Ovidiu BochisDepartment of Medical Oncology, The Oncology Institute "Prof. Dr. Ion Chiricuţă" Cluj-Napoca, Cluj-Napoca, ROU.
Rares BuigaDepartment of Pathology, The Oncology Institute "Prof. Dr. Ion Chiricuţă" Cluj-Napoca, Cluj-Napoca, ROU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of incidental masses in cancer patients, such as vulvar leiomyomas, is rare and can complicate the diagnostic process. We report a case of a 62-year-old woman who presented with a large, neglected breast tumor, which raised clinical suspicion of metastatic breast cancer. A computed tomography scan showed an osteosclerotic pelvic lesion, raising concern for bone metastasis. A whole-body positron emission tomography scan revealed no bone metastasis but detected a hypermetabolic left vulvar mass, presumed to be a Bartholin cyst. Surgical excision confirmed it to be a vulvar leiomyoma. The patient underwent neoadjuvant chemotherapy for breast cancer, followed by a left radical mastectomy with significant residual tumor burden. Currently, the patient is receiving radiotherapy along with adjuvant hormonal treatment, and CDK4/6 inhibitor therapy is scheduled after the radiotherapy. When found incidentally during cancer staging, vulvar leiomyomas can cause diagnostic confusion. This case highlights the importance of a comprehensive and multidisciplinary differential diagnostic approach in the oncological assessment of cancer patients to avoid misdiagnosis and guide appropriate treatment strategies.

Indexed as

breast cancercase reportdifferential diagnosisvulvar leiomyomavulvar mass

Identifiers

PMID40458368
PMCPMC12129436

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.