Evidence map›Paper›PMID 40458183›Full record

ArticleFrontiers in adolescent medicine2025

Substance Use and Social Influence as Risk Factors for Nicotine and Tobacco Product Use in Adolescents and Young Adults who use Electronic Nicotine Delivery Systems.

Laura E Hatz, Kelly E Courtney, Alexander L Wallace, Natasha E Wade, Rachel Baca, Neal Doran, Joanna Jacobus

Abstract read
In one paragraph

Article in Frontiers in adolescent medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Laura E HatzDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Kelly E CourtneyDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Alexander L WallaceDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Natasha E WadeDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Rachel BacaDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Neal DoranDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.
Joanna JacobusDepartment of Psychiatry, University of California San Diego, La Jolla, CA, USA.

Funding

ABCD-USA Consortium: Research ProjectU01DA041089 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus, Susan F. Tapert · 2015 to 2026
$31.7M
Alcohol Research in the Science/Practitioner ModelT32AA013525 · NIAAA · SAN DIEGO STATE UNIVERSITY · PI EDWARD P RILEY, ANDREA SPADONI TOWNSEND · 2002 to 2026
$8.4M
Cannabis and Nicotine Co-Use Influences on Protracted Development of Neural Structure and FunctionR01DA054106 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Joanna Jacobus · 2021 to 2026
$3.2M
Vaping in Childhood and Adolescence: Cognitive and Behavioral ConsequencesR01DA054980 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Neal Doran, Joanna Jacobus · 2022 to 2026
$1.4M
Effects of Comorbid Cannabis and Tobacco Product Use on Adolescent NeurodevelopmentR21DA047953 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JACOBUS, JOANNA · 2019 to 2020
$433k
NIAAA NIH HHS T32 AA013525NIDA NIH HHS R01 DA054106NIDA NIH HHS R01 DA054980NIDA NIH HHS R21 DA047953NIDA NIH HHS U01 DA041089
6 · The paper itself

Abstract

Background: Nicotine and tobacco product (NTP) use in adolescence and young adulthood is associated with negative health and psychosocial outcomes. This study prospectively tested alcohol use, cannabis use, and peer and family NTP use as predictors of NTP use in adolescents and young adults (AYAs) who were NTP naïve or who primarily used electronic nicotine delivery systems (ENDS). Method: Participants (N=133) ages 16-22 completed a baseline laboratory visit and follow-up session one year later. Participants' baseline alcohol use, cannabis use, and NTP use by peers and family were tested as risk factors for any and moderate to heavy (at least monthly) NTP use at follow-up. Logistic regressions were conducted for the full sample (N=133) and in a subsample of participants reporting no to low NTP use at baseline (n=76). Results: Baseline alcohol use, cannabis use, and peer and family NTP use were associated with NTP use at one-year follow-up, over and above baseline NTP use. Peer and family NTP use emerged as the most consistent predictor of AYA NTP use (ORs: 4.059 - 8.432), while recent cannabis and alcohol use exerted effects (ORs: 1.003 - 1.021) that varied by NTP use level. Discussion: A confluence of variables, including prior substance use and social and familial influences, act as risk factors for NTP use in AYAs who primarily use ENDS. Identification of risk and protective factors for NTP use is necessary to inform efforts to decrease NTP use in this developmentally vulnerable population.

Indexed as

adolescentsalcoholcannabisnicotinerisk factorsyoung adults

Identifiers

PMID40458183
PMCPMC12129052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.