ArticleFrontiers in endocrinology2025
Molecular and clinical profiles of T2DM, dyslipidemia, and periodontitis: insights into inflammatory and metabolic dysregulation.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Article
- Inflammatory Load Across Diabetes Duration: CRP and ESR Patterns and Their Metabolic Correlates.Metabolites · 2026Article
- Interrelationship Between Dyslipidemia and Hyperuricemia in Patients with Uncontrolled Type 2 Diabetes: Clinical Implications and a Risk Identification Algorithm.Healthcare (Basel, Switzerland) · 2025Article
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6 authors.
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Abstract
Introduction: Type 2 Diabetes Mellitus (T2DM), dyslipidemia, and periodontitis are interconnected conditions that exacerbate systemic inflammation and metabolic dysregulation. Understanding the molecular and clinical profiles of these comorbidities is crucial for developing targeted interventions. This study investigates the molecular and clinical profiles of individuals with T2DM, dyslipidemia, and periodontitis to identify key markers and pathways underlying disease severity and progression. Methods: Peripheral blood mononuclear cells (PBMCs) were analyzed from five patient groups: T2DM poorly controlled with dyslipidemia and periodontitis (T2DMpoorly-DLP-H), T2DM well-controlled with dyslipidemia and periodontitis (T2DMwell-DLP-H), dyslipidemia and periodontitis (DL-P), periodontitis alone (P), and healthy controls (H). Correlations between molecular and clinical markers were assessed. Results: The T2DMpoorly-DLP-H group exhibited the most extensive molecular dysregulation, including unique upregulation of Discussion: This study identifies
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