ArticleScience progress
Association between vitamin D levels and thyroid function tests in euthyroid women with obesity.
Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ObjectiveThyroid hormones are essential for energy expenditure and metabolism, and their dysfunction is associated with obesity. Vitamin D, besides its role in bone health, may influence thyroid function, especially in women with obesity, where deficiency is common and linked to altered thyroid hormone levels and sensitivity. This study aimed to investigate the relationship between vitamin D levels and thyroid function tests (TFTs) in euthyroid women with obesity.MethodsThis single-center, cross-sectional study was conducted in the obesity center of a tertiary hospital in Turkey, between July and September 2024. Women with a body mass index of 30 or higher and confirmed to be euthyroid based on TFTs were included, while those receiving thyroid medications or lacking concurrent 25-hydroxyvitamin D (25(OH)D) measurements were excluded. Data were collected retrospectively from the hospital's information management system, and participants were categorized into three groups based on their 25(OH)D levels (<20 ng/mL, 20-29.9 ng/mL, ≥ 30 ng/mL).ResultsThe study included 158 participants. No significant associations were observed between thyroid stimulating hormone (TSH) levels and participant characteristics or 25(OH)D levels. In contrast, thyroxine (T4) levels were significantly higher in participants with diabetes mellitus (DM), those without psychiatric disorders, and those with 25(OH)D levels of 30 ng/mL or higher compared to others. ANCOVA analysis adjusted for DM and psychiatric disorders confirmed significant differences in T4 levels among the 25(OH)D groups.ConclusionThis study suggests that vitamin D levels may be associated with T4 levels in euthyroid women with obesity. Although no link was found with TSH, the findings suggest that further research is needed on the potential role of vitamin D in thyroid function. These preliminary findings may also highlight the clinical relevance of monitoring and managing vitamin D levels in individuals with obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.