ReviewHuman vaccines & immunotherapeutics2025
Translational horizons in bacterial membrane vesicles: Hotspots and frontiers from basic medicine to clinical application by bibliometric analysis.
Review in Human vaccines & immunotherapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial membrane vesicles (BMVs) represent a class of nanoscale lipid particles released by both Gram-positive and Gram-negative bacteria, serving as versatile mediators of intercellular communication and host-pathogen interactions. Their unique biogenesis pathways and functional properties have positioned them as promising targets for therapeutic and biotechnological applications. To comprehensively assess the research trends of this dynamic research field, we conducted a bibliometric analysis of 6,352 studies on BMVs published between 1 January 2014 and 19 November 2024 using VOSviewer, CiteSpace, and the R package "bibliometrix." Our analysis revealed that the Chinese Academy of Sciences led institutional contributions, while Frontiers in Microbiology emerged as the most active journal. Kim, Yoon-Keun was the most prolific author, reflecting his significant influence in the field. Key research hotspots were categorized into four frontiers: biogenesis mechanisms, pathogenesis and immune regulation, clinical applications, and methodological and engineering innovations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.