Evidence map›Paper›PMID 40457793›Full record

ReviewZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2025

Research progress in the role of tubal ciliary movement in female infertility-related disorders.

Liuqing He, Yefang Huang, Haofei Xu, Xiaoxiao Yin, Xinyu Luo, Shiyu Huang

Abstract readReview
In one paragraph

Review in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. An exploratory study on the impact of endocrine and infectious comorbidities on reproductive outcomes after Palmer-type neosalpingostomy.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Liuqing HeDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China. 342266194@qq.com.
Yefang HuangDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China. huangyefang@cdutcm.edu.cn.
Haofei XuDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Xiaoxiao YinDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Xinyu LuoDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Shiyu HuangDepartment of Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.

Funding

the Key Research and Development Project of Sichuan Provincial Department of Science and Technology 2022YFS0415
6 · The paper itself

Abstract

Tubal ciliary movement is one of the essential transport mechanisms for female fertility, playing a key role in facilitating oocyte pickup and transporting the fertilized ovum. This movement is mediated by multiciliated cells and regulated by specific proteins and hormones that modulate ciliary number, length, polarity, beat frequency, and amplitude to ensure proper function. Genetic mutations, inflammatory stimuli, and hormonal fluctuations can impair ciliary activity or induce ciliary apoptosis, leading to ciliary dysfunction. Disorders of tubal ciliary movement are frequently observed in primary ciliary dyskinesia, pelvic inflammatory disease, polycystic ovary syndrome, and endometriosis, conditions commonly associated with female infertility. These disorders manifest as structural abnormalities of cilia, disrupted polarity, shortened ciliary length, reduced ciliary count, and decreased beat frequency and amplitude. Understanding the role of tubal ciliary movement in female infertility-related diseases, through immunohistochemistry and ultrastructural analysis, helps clarify underlying infertility mechanisms. Identifying abnormal inflammatory factors, hormonal environments, and gene expression, combined with advanced techniques for measuring ciliary protein and beat frequency, may offer novel clinical targets for early prevention and treatment of female infertility.

Indexed as

CiliaFallopian TubesInfertility, FemaleEndometriosisFemaleHumansPelvic Inflammatory DiseasePolycystic Ovary Syndromecellular structureciliary polarityfallopian tube ciliafemale infertilitymotile cilia

Identifiers

PMID40457793
PMCPMC13346025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.