Evidence map›Paper›PMID 40457726›Full record

ArticlePhysiological reports2025

Characterization of dysfunctional breathing using cardiopulmonary exercise testing.

Sebastian F Möbus, Chris J Harding, Catherine L Taylor, Karl P Sylvester, Jonathan P Fuld

Abstract read
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sebastian F MöbusSchool of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID 0009-0008-7738-6833
Chris J HardingLung Function Unit, Cambridge University Hospitals NHSFT, Cambridge, UK.
Catherine L TaylorSports and Exercise Medicine, East Suffolk and North Essex NHSFT, Ipswich, UK.
Karl P SylvesterRespiratory Physiology, Royal Papworth Hospital NHSFT, Cambridge, UK.ORCID 0000-0001-6851-1219
Jonathan P FuldVictor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiopulmonary exercise testing (CPET) is emerging as a useful tool in the identification of dysfunctional breathing (DB). We aimed to evaluate the prevalence and functional impact of different patterns of DB in 628 adult patients referred for CPET due to unexplained dyspnoea (August 2019-December 2023). Patients were assigned to four groups following CPET interpretation: normal, breathing pattern disorder (BPD), hyperventilation (HV), and combined BPD with HV (BPDHV). Demographic and CPET performance data were analyzed using non-parametric tests as appropriate. 94 (15.0%) patients had normal CPETs and 267 (42.5%) were identified as having DB. The remaining 267 were excluded as having alternative diagnoses. Of those with DB, 145 (54.3%) had BPD, 41 (15.4%) had HV, and 81 (30.3%) had BPDHV. VE/VCO

Indexed as

DyspneaExercise TestHyperventilationRespiration DisordersAdultAgedFemaleHumansMaleMiddle AgedOxygen Consumptionbreathing pattern disordercardiopulmonary exercise testingdysfunctional breathingdyspnoeaexercise capacityhyperventilation

Identifiers

PMID40457726
PMCPMC12130561

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.