Evidence map›Paper›PMID 40457640›Full record

ArticleBiophysical journal2025

Effects of open-channel blocking peptides in Na

Maria Riedersberger, Madalina Woltereck, Paul J Wagner, Kristin Focke, Sarina Höller, Angelika Lampert, Christian Alzheimer, Stefan Düsterhöft, Tobias Huth

Abstract read
In one paragraph

Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maria RiedersbergerInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Madalina WoltereckInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Paul J WagnerInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Kristin FockeInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Sarina HöllerInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Angelika LampertInstitut für Neurophysiologie, Universitätsklinikum RWTH Aachen University, Aachen, Germany.
Christian AlzheimerInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany.
Stefan DüsterhöftInstitute of Molecular Pharmacology, Universitätsklinikum RWTH Aachen University, Aachen, Germany. Electronic address: sduesterhoeft@ukaachen.de.
Tobias HuthInstitut für Physiologie und Pathophysiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany. Electronic address: tobias.huth@fau.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resurgent sodium currents (INaRs) result from an unorthodox gating behavior of voltage-activated sodium channels (Na

Indexed as

Ion Channel GatingNAV1.5 Voltage-Gated Sodium ChannelPeptidesAmino Acid SequenceFibroblast Growth FactorsHEK293 CellsHumansfibroblast growth factor 14Fibroblast Growth FactorsNAV1.5 Voltage-Gated Sodium ChannelPeptidesSCN5A protein, human

Identifiers

PMID40457640
PMCPMC12414692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.