ArticleCNS neuroscience & therapeutics2025
CXCL10
Article in CNS neuroscience & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- CCL5 and CD11b-fibrin interactions regulate microglia migration and morphology in hyperinflammatory experimental cerebral malaria.Journal of neuroinflammation · 2026Article
- Microglia and neuroinflammation: function, heterogeneity, and crosstalk.Cellular & molecular immunology · 2026Review
- Splenic macrophage-B cell axis drives systemic autoimmune-like pathology in Cerebral Malaria.Nature communications · 2026Article
- The Future of Protozoan Infection Research: 3D Cell Culture and beyond.ACS infectious diseases · 2026Review
- CXCL10CNS neuroscience & therapeutics · 2026Article
- Hemozoin induces neuronal injury primarily characterized by axon rupture and mitochondrial damage in experimental cerebral malaria.Parasites & vectors · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors.
Funding
Abstract
aimsThis study aimed to investigate the heterogeneity of microglia and their role in recruiting and activating CD8
methodsC57BL/6J mice were infected with Plasmodium berghei ANKA (PbA) to induce ECM. Morphology and distribution of microglia were assessed via immunofluorescence (IF) staining and electron microscopy. Single-cell RNA-sequencing (scRNA-seq) analyzed the activation characteristics of infiltrating CD8
resultsIn vivo, microglia were aggregated in the brainstem and olfactory bulb in the ECM brain, regions that exhibited more severe pathological injury. The transcriptional characteristics of ECM microglia distinguished from physiological microglia and exhibit morphological heterogeneity in the ECM brain. Infiltrating CD8
conclusionsOur study identified an ECM-associated microglia subtype and explored its interaction with CD8
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.