Evidence map›Paper›PMID 40457485›Full record

ArticleBMC sports science, medicine & rehabilitation2025

Nutritional status in subacute post-stroke patients undergoing rehabilitation treatment: a protocol for a prospective observational study.

Mariacristina Siotto, Carola Cocco, Alessandro Guerrini, Chiara Bertoncini, Marco Germanotta, Valeria Cipollini, Laura Cortellini, Arianna Pavan, Stefania Lattanzi, Caterina Galluccio and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in BMC sports science, medicine & rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06096350 (Study of Nutritional Status in Subacute Stroke Patients Under Rehabilitation Treatment), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06096350 unknown statusnot on this map

Study of Nutritional Status in Subacute Stroke Patients Under Rehabilitation Treatment

TypeobservationalSponsorFondazione Don Carlo Gnocchi ETSRan2024 to 2025Enrolled55ConditionsStrokeArmsrobotic assisted intervention, hematochemical analysis, BIA, hand grip, nutritional assessment, MNA,, stool sampling
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mariacristina SiottoIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy. msiotto@dongnocchi.it.
Carola CoccoIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Alessandro GuerriniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Chiara BertonciniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Marco GermanottaIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Valeria CipolliniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Laura CortelliniIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Arianna PavanIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Stefania LattanziIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Caterina GalluccioIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Sabina InsalacoIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Erika AntonacciIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Elisabetta RucoIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.
Irene Giovanna AprileIRCCS Fondazione Don Carlo Gnocchi ONLUS, Florence, 50143, Italy.

Funding

Ministero della Salute- Minister of Health-PSC SALUTE 2014-2020 - Traiettoria 5 - "Nutraceutica, nutrigenomica e alimenti funzionali" projecy: "IDENTITA - rete Integrata meDiterranea per l'osservazione ed Elaborazione di percorsi di Nutrizione personalizzaTa contro la malnuTrizione" (T5-AN-01). T5-AN-01
6 · The paper itself

Abstract

backgroundRecent developments in clinical nutrition emphasise the value of early intervention and proper nutritional management and the significance of a multidisciplinary approach to the treatment of post-stroke patients. A recent study by our research group demonstrated the correlation between nutritional status and recovery in post-stroke patients during rehabilitation. This protocol aims to examine and delineate in detail the nutritional status of subacute post-stroke patients before and after the rehabilitation treatment.

methodsThis clinical study is a monocentric prospective longitudinal observational research project. The aim of the protocol described herein is to assess the nutritional status, both on admission (T0) and after six weeks of rehabilitation treatment (T1), in a cohort of subacute stroke patients. In addition to clinical evaluations, we will determine anthropometric measurements, malnutrition will be diagnosed as for Global Leadership Initiative on Malnutrition (GLIM) criteria, and food intake will be registered combined with bromatological analysis. Bioelectrical impedance analysis (BIA) will be conducted to evaluate body composition, while sarcopenia will be diagnosed following the European Working Group on Sarcopenia in Older People (EWGSOP2) guidelines. Metabolic status will be assessed through indirect calorimetry and haematochemical analyses. As a secondary outcome, the correlation between the aforementioned assessments and rehabilitation outcomes will be examined. DISCUSSION: This document outlines the protocol "Nutritional Status in Subacute Stroke Patients Undergoing Rehabilitation", which aims to assess rigorously and more specifically the nutritional status. The advantage of this study is that nutritional assessment will include numerous instrumental and biological analyses, providing a comprehensive and exhaustive assessment of patients' nutritional status on admission and after six weeks of rehabilitation. This will provide information about the correct assessment and monitoring of the nutritional status of post-stroke patients during hospitalization for rehabilitation. It is of utmost importance to avoid the increasing risk of complications associated with undiagnosed malnutrition and sarcopenia during the months of hospitalisation for rehabilitation. TRIAL REGISTRATION NUMBER: NCT06096350 (ClinicalTrials.gov), date of registration: 23/10/2023.

Indexed as

DysphagiaFood consumptionGut microbiotaMalnutritionNutritional statusOxidative stressPost-strokeRehabilitationSarcopenia

Identifiers

PMID40457485
PMCPMC12128303

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.