Evidence map›Paper›PMID 40457308›Full record

ArticleBMC urology2025

Double-J stenting during TURBT increases risk of metachronous upper tract urothelial carcinoma.

Zhengfeng Wu, Canhui Qu, Guangyao Liang, Rui Sun, Nanhe Lin, Yun Xie, Huanqing Wei, Jianfeng Guan, Chengqiang Mo

Abstract read
In one paragraph

Article in BMC urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhengfeng Wu *Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Canhui Qu *Department of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Guangyao LiangZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Rui SunZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, 510080, China.
Nanhe LinDepartment of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Yun XieDepartment of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Huanqing WeiDepartment of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China.
Jianfeng GuanDepartment of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. guanjianf@mail3.sysu.edu.cn.
Chengqiang MoDepartment of Urology, The First Affiliated Hospital of Sun Yat-sen University, No. 58, Zhongshan 2nd Road, Guangzhou, 510080, Guangdong, China. mochengq@mail.sysu.edu.cn.

Funding

Natural Science Foundation of Guangdong Province 2024A1515010094
6 · The paper itself

Abstract

objectiveThe potential impact of double-J (DJ) stenting during transurethral resection of bladder tumor (TURBT) on the occurrence of metachronous upper urinary tract urothelial carcinoma (UTUC) remains a subject of debate. This study investigates the effect of DJ stenting during TURBT for bladder cancer (BC) on the incidence of metachronous UTUC.

methodsWe retrospectively analyzed the data from patients who underwent TURBT at our institution between September 2013 and September 2023. Patients were grouped based on whether DJ stents were placed during TURBT. The outcome was the occurrence of metachronous UTUC, defined by UTUC occurring 3 months after TURBT. We define UTUC in DJ group occurring 3 months to 24 months post-TURBT as stent-related metachronous UTUC. Propensity scores adjustment was computed to control the confounding factors (p < 0.05). Kaplan-Meier analyses estimated metachronous UTUC recurrence-free survival (RFS) before and after propensity scores adjustment. Cox regression analyses were used to evaluate the data. Subgroup analyses and interaction tests for all categorical variables were conducted.

resultsA total of 570 patients were included in this study. We identified 19 (3.33%) patients were metachronous UTUC. Among patients with metachronous UTUC, 7 patients received DJ stents, while 12 patients did not receive DJ stents. Kaplan-Meier analysis showed poorer recurrence-free survival in the DJ group during the first two years postoperatively (unadjusted p < 0.001 VS. adjusted p = 0.006) and throughout the entire follow-up period (unadjusted p < 0.001 VS. adjusted p < 0.001). Cox multivariable regression analysis revealed that the placement of DJ stent was an independent risk factor for metachronous UTUC-free survival rates within the first two years postoperatively ( p = 0.003) or during the overall follow-up period ( p < 0.001).

conclusionsPatients who underwent DJ stenting during TURBT for BC exhibited an increased risk of developing metachronous UTUC, suggesting a potential association that warrants further investigation.

Indexed as

Carcinoma, Transitional CellCystectomyKidney NeoplasmsNeoplasms, Second PrimaryStentsUreteral NeoplasmsUrinary Bladder NeoplasmsAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsBladder cancerDouble J stentPropensity score adjustmentTransurethral resection of bladder tumorUpper urinary tract urothelial carcinoma

Identifiers

PMID40457308
PMCPMC12128326

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.