Evidence map›Paper›PMID 40457260›Full record

ArticleBMC psychiatry2025

Bridge symptoms of insomnia, obsessive-compulsive symptoms, and depression/anxiety: a network analysis.

Shiqi Yuan, Ruiyang Wang, Yongyan Shi, Yixin Zhao, Haojuan Tao, Guowei Wu, Liwen Tan, Xuan Ouyang

Abstract read
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shiqi Yuan *Department of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Ruiyang Wang *Department of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Yongyan ShiDepartment of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Yixin ZhaoDepartment of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Haojuan TaoDepartment of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Guowei WuDepartment of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China.
Liwen TanDepartment of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China. tanliwen@csu.edu.cn.
Xuan OuyangDepartment of Psychiatry, National Clinical Research Center for Mental Disorders and National Center for Mental Disorders, The Second Xiangya Hospital of Central South University, Changsha, Hunan, 410011, China. ouyangxuan@csu.edu.cn.

Funding

STI2030-Major Projects 2021ZD0201900
6 · The paper itself

Abstract

backgroundInsomnia has been associated with obsessive-compulsive disorder (OCD), as well as depression and anxiety. However, their interactions and the influence of depression and anxiety on this relationship remain unclear. We aimed to assess the bridge and central symptoms of the insomnia-obsessive-compulsive (OC) network model and explore the impact of depression and anxiety on these connections.

methodsA total of 1,046 patients were included in our study. The severity of insomnia, OC, depression, and anxiety were measured using the Pittsburgh Sleep Quality Index, Yale-Brown Obsessive-Compulsive Scale, Zung's Self-Rating Anxiety Scale, and Zung's Self-Rating Depression Scale, respectively. Stability analyses of marginal weights were conducted to assess network robustness.

resultsThe network analysis revealed that compulsive behaviors and low sleep quality were shown to be the most central symptoms in the insomnia-OC network, with compulsive behaviors and daytime dysfunction acting as bridge symptoms. Daytime dysfunction, obsessive thoughts, anxiety and panic were found to be bridge symptoms in the insomnia-OC-anxiety network. In the insomnia-OC-depression network, daytime dysfunction, obsessive thoughts, and rhythm disturbances were possible bridge symptoms.

conclusionsCompulsive behaviors and daytime dysfunction were linked to insomnia and OC. In the insomnia-OC-anxiety network, anxiety and panic played a central role, while depressed mood was prominent in the insomnia-OC-depression network model. Targeting compulsive behaviors and improving daytime functioning may help reduce insomnia in individuals with OCD. Additionally, addressing anxiety and panic, and rhythm disturbances may further alleviate the psychological distress in these patients.

Indexed as

AnxietyDepressionObsessive-Compulsive DisorderSleep Initiation and Maintenance DisordersAdultFemaleHumansMaleMiddle AgedYoung AdultAnxietyBridge symptomsDepressionInsomniaNetwork analysisObsessive-compulsive disorder (OCD)

Identifiers

PMID40457260
PMCPMC12131647

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.