Evidence map›Paper›PMID 40457222›Full record

ArticleBMC gastroenterology2025

Global, regional, and national burden of inflammatory bowel disease in persons aged 60-89 years from 1992 to 2021.

Zhou Zhang, Na Du, Chun-Mei Xu, Wei Chen, Ting-Ting-Chen, Yu Xiao

Abstract read
In one paragraph

Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Use of Upadacitinib in elderly patients with IBD: a case series.Journal of pharmaceutical health care and sciences · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhou ZhangDepartment of Gastroenterology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, 15 Liberation Road, Xiangyang, 441000, People's Republic of China.ORCID http://orcid.org/0009-0007-9193-9193
Na DuPsychosomatic Medical Center, The Fourth People's Hospital of Chengdu, No.8, Huli West Lane 1, Yingmenkou Road, Chengdu, 610036, People's Republic of China.
Chun-Mei XuDepartment of Gastroenterology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, 15 Liberation Road, Xiangyang, 441000, People's Republic of China.
Wei ChenDepartment of Gastroenterology, Xiangyang No.1 People's Hospital, Hubei University of Medicine, 15 Liberation Road, Xiangyang, 441000, People's Republic of China.
Ting-Ting-ChenMental Health Center, West China Hospital of Sichuan University, Chengdu, 610044, People's Republic of China.
Yu XiaoPsychosomatic Medical Center, The Fourth People's Hospital of Chengdu, No.8, Huli West Lane 1, Yingmenkou Road, Chengdu, 610036, People's Republic of China. xiaoy3@outlook.com.ORCID http://orcid.org/0000-0003-2216-9686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global burden of inflammatory bowel disease (IBD) is increasing, but detailed data on older adults remain scarce.

objectiveThis study describes trends in incidence, prevalence, mortality, and disability-adjusted life years (DALYs) of IBD among individuals aged 60-89 years from 1992 to 2021 at global, regional, and national levels, and forecasts the epidemiological status for 2030.

methodsWe used the Global Burden of Disease (GBD) database, covering 204 countries and territories. Temporal trends were analyzed using Joinpoint regression models. Decomposition analysis assessed the impacts of population growth, aging, and epidemiological changes. The Nordpred model forecasted 2030 incidence, prevalence, mortality, and DALYs of IBD among older adults.

resultsFrom 1992 to 2021, the global age-standardized incidence rate (ASIR) of IBD among older adults increased (AAPC 0.34). Conversely, the prevalence rate (ASPR) slightly decreased (AAPC - 0.04). Both mortality (ASMR) and DALYs significantly declined (AAPC - 0.60 and - 0.49, respectively). High SDI regions had the highest ASIR and ASPR, with Middle SDI regions experiencing the fastest ASIR growth. Population growth accounted for 117.77% of the overall increase in the IBD burden. By 2030, the incidence rate is expected to rise, but prevalence, mortality, and DALYs rates are predicted to decrease.

conclusionThe incidence rate of IBD among older adults is rising, while prevalence, mortality, and DALYs rates are declining. Significant regional variations underscore the need for targeted public health policies.

Indexed as

Global Burden of DiseaseInflammatory Bowel DiseasesAgedAged, 80 and overDisability-Adjusted Life YearsFemaleGlobal HealthHumansIncidenceMaleMiddle AgedPrevalenceDisease burdenGlobal epidemiologyInflammatory bowel diseaseSociodemographic index

Identifiers

PMID40457222
PMCPMC12131378

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.