ArticleEJNMMI research2025
Clinical effect of three-dimensional left ventricular mechanical dyssynchrony and cardiac sympathetic denervation in systolic heart failure risk-stratified by left ventricular ejection fraction and QRS duration.
Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe left ventricular ejection fraction (LVEF) and QRS duration (QRSd) are prognostic factors in patients with systolic heart failure (HF). However, no study has evaluated the prognosis was evaluated by adding three-dimensional left ventricular mechanical dyssynchrony (LVMD) and cardiac sympathetic dysfunction.
resultsIn 1011 consecutive patients with HF having LVEF < 50%, LVMD was evaluated as the phase SD of the regional onset-of-mechanical contraction phase angles on a phase histogram created by Fourier phase analysis applied to regional time-activity curves obtained by gated myocardial perfusion.
conclusionsThe addition of three-dimensional LVMD and cardiac sympathetic function to the evaluation of LVEF and QRSd in patients with systolic HF may stratify the risk of their prognosis.
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