Evidence map›Paper›PMID 40457048›Full record

ArticleScientific reports2025

A simulation study on the temperature-dependent release of endocrine-disrupting chemicals from polypropylene and polystyrene containers.

Tooraj Massahi, Abdullah Khalid Omer, Amir Kiani, Borhan Mansouri, Hamed Soleimani, Nazir Fattahi, Masoud Moradi, Kiomars Sharafi

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tooraj MassahiStudent Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Abdullah Khalid OmerSmart Health Tower, Madam Mitterrand Street, Sulaymaniyah, Kurdistan, 46001, Iraq.
Amir KianiRegenerative Medicine Research Center (RMRC), Kermanshah University of Medical Sciences, Kermanshah, Iran.
Borhan MansouriSubstance Abuse Prevention Research Center, Research Institute for Health, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Hamed SoleimaniDepartment of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Nazir FattahiResearch Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Masoud MoradiResearch Center for Environmental Determinants of Health (RCEDH), Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Kiomars SharafiSocial Development and Health Promotion Research Center, Health Policy and Promotion Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran. kio.sharafi@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the ubiquity of plastic packaging, this study evaluated the release of endocrine-disrupting chemicals (EDCs) into liquid foods at various temperatures. Solid-phase extraction (SPE) and gas chromatography-mass spectrometry (GC/MS) methods were used to identify EDCs, including phthalates (BBP, DEHP, DBP), bisphenol A (BPA), and nonylphenol (NP) from cups and containers made of polypropylene (PP) and general-purpose polystyrene (GPPS). The distilled water in PP and GPPS contained no EDCs at 4-10 °C. DEHP, DBP, BBP, BPA, and NP were found in water contained in PP cups and containers at higher temperatures (40-100 °C), with DEHP released the most at 100 °C (1242.5 ± 53.0 ng/L and 1615.3 ± 68.9 ng/L) for water contained in cups and containers, respectively. No BPA, DBP, or BBP was found in the contents of GPPS cups or containers at any temperature. The average EDCs released from PP cups and containers at every storage temperature was significantly higher (P < 0.001) than GPPS. These findings highlight the importance of temperatures and material composition in plastic packaging for food safety. Consumers should be careful when using plastic cups and containers, especially at higher temperatures, as EDC release can pose health risks.

Indexed as

Endocrine DisruptorsFood PackagingPolypropylenesPolystyrenesBenzhydryl CompoundsBisphenol A CompoundsFood ContaminationGas Chromatography-Mass SpectrometryPhenolsPhthalic AcidsSolid Phase ExtractionTemperatureBenzhydryl Compoundsbisphenol ABisphenol A CompoundsEndocrine DisruptorsPhenolsPhthalic AcidsPolypropylenesPolystyrenesBisphenol AEndocrine-disrupting chemicalsGeneral-purpose polystyrenePhthalatePolypropylene

Identifiers

PMID40457048
PMCPMC12130511

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.