Evidence map›Paper›PMID 40457016›Full record

ArticleNPJ digital medicine2025

Randomized comparison of AI enhanced 3D printing and traditional simulations in hepatobiliary surgery.

Linqian Li, Shujie Cheng, Jinghua Li, Jihong Yang, Hongguang Wang, Bin Dong, Xiaoping Yin, Hongyun Shi, Shuo Gao, Feng Gu and 8 more

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. [Minimally invasive liver resection-New techniques].Chirurgie (Heidelberg, Germany) · 2026
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  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Linqian Li *Surgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Shujie ChengSurgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China. chengshuj@126.com.
Jinghua LiSurgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China. 1666214806@qq.com.
Jihong Yang *Basic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Hongguang WangDepartment of Hepatobiliary Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. wanghongguang301@163.com.
Bin Dong *Surgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Xiaoping Yin *Surgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Hongyun Shi *Surgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Shuo Gao *Basic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Feng Gu *Basic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Zhe HanSurgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China.
Zhi ChenBasic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Jisen ZhaoBasic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Quan ZhangBasic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Jie-Zhi ChengUnited Imaging Intelligence, Shanghai, China.
Yuan WangBasic Research Key Laboratory of General Surgery for Digital Medicine, Baoding, Hebei Province, China.
Fengwei TanDepartment of Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. tanfengwei@126.com.
Ke ZhangSurgical Department, Affiliated Hospital of Hebei University, Baoding, Hebei Province, China. 93391@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We employed a three-phase approach, culminating in a randomized controlled trial, to assess the efficacy of 3D-printed liver models in hepatobiliary surgical planning. Phase one involved developing and selecting 35 optimal 3DP models based on timeliness, cost, precision, and alignment with digital simulations. Phase two utilized deep learning algorithms to optimize the 3D reconstruction process, significantly enhancing efficiency and accuracy compared to manual segmentation. In phase three, a randomized controlled trial with 64 patients compared surgical outcomes between those planned with AI-enhanced physical 3DP models and those with traditional digital simulations. Results demonstrated that 3DP models were produced rapidly (3.52 h at $152 each) with high precision, AI-assisted reconstruction reduced processing time (303.5 vs. 557 min), and patients using AI-enhanced physical 3DP models experienced less intraoperative blood loss. Integrating deep learning with 3D printing offers a cost-effective, scalable method to enhance surgical planning and outcomes in hepatobiliary surgery.

Identifiers

PMID40457016
PMCPMC12130338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.