Evidence map›Paper›PMID 40456889›Full record

ArticleScientific reports2025

The correlation analysis of weight and blood pressure during the pregnancy and its influencing factors: a retrospective study.

Jie Ren, Jing Li, Zhuoran Fan, Caiyun Zhao, Yujie Wang, Shaofang Hua

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jie RenThe obstetrics department of Tianjin Medical University the Second Hospital, Pingjiang Road, No.23, Hexi district, 300211, Tianjin, China.
Jing LiThe obstetrics department of Tianjin Medical University the Second Hospital, Pingjiang Road, No.23, Hexi district, 300211, Tianjin, China.
Zhuoran FanThe obstetrics department of Tianjin Medical University the Second Hospital, Pingjiang Road, No.23, Hexi district, 300211, Tianjin, China.
Caiyun ZhaoThe obstetrics department of Tianjin Medical University the Second Hospital, Pingjiang Road, No.23, Hexi district, 300211, Tianjin, China.
Yujie WangThe obstetrics department of Tianjin Medical University the Second Hospital, Pingjiang Road, No.23, Hexi district, 300211, Tianjin, China.
Shaofang HuaThe obstetrics department of Tianjin Medical University the Second Hospital, Pingjiang Road, No.23, Hexi district, 300211, Tianjin, China. hsf1974@126.com.

Funding

the Natural Science Funds of Tianjin Education Commission 2020KJ171Tianjin Medical University the Second Hospital Youth Foundation 2023ydey05
6 · The paper itself

Abstract

This study aimed to evaluate the correlation between maternal weight and blood pressure during pregnancy and determine the magnitude of blood pressure changes per kilogram of weight gained. Additionally, we investigated whether this relationship differs among women with gestational diabetes mellitus (GDM) and various categories of hypertensive disorders of pregnancy. This retrospective cohort study analyzed 4,051 pregnancies delivered at Tianjin Medical University Second Hospital between January 2019 and December 2020. We performed covariance analysis controlling for maternal age, gestational weight gain, and neonatal birthweight, followed by simple linear regression to quantify blood pressure changes per kilogram of maternal weight. Subgroup analyses examined these relationships in women with and without GDM, chronic hypertension (CH), gestational hypertension (GH), and normotensive pregnancies. A moderate correlation existed between maternal weight and both systolic (r = 0.427, p < 0.001) and diastolic (r = 0.397, p < 0.001) blood pressure. Each kilogram increase in maternal weight was associated with a 0.47mmHg increase in systolic and 0.325mmHg increase in diastolic blood pressure. These correlations were comparable between women with and without GDM (r = 0.411 vs. r = 0.406 for systolic; r = 0.392 vs. r = 0.372 for diastolic blood pressure). However, correlations were notably attenuated in women with chronic hypertension (r = 0.202 for systolic; r = 0.095 for diastolic blood pressure) compared to those with gestational hypertension or normotensive pregnancies. Maternal weight demonstrates a moderate correlation with blood pressure during pregnancy, with greater impact on systolic than diastolic parameters. This relationship remains consistent regardless of gestational diabetes status but is significantly diminished in women with chronic hypertension. Appropriate weight management may contribute to blood pressure control during pregnancy, particularly for women without pre-existing hypertensive disease.

Indexed as

Blood PressureDiabetes, GestationalGestational Weight GainAdultBirth WeightFemaleHumansHypertensionHypertension, Pregnancy-InducedPregnancyRetrospective StudiesBlood pressureMetabolic disturbanceObesityPregnancyWeight control

Identifiers

PMID40456889
PMCPMC12130466

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