ArticleNature food2025
High diversity of dietary flavonoid intake is associated with a lower risk of all-cause mortality and major chronic diseases.
Article in Nature food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- Maternal Dietary Anthocyanidin, Dietary Inflammatory Potential, and Risk of Small-for-Gestational-Age in China.Nutrients · 2025Trial
- Flavonoid intake and telomere length attrition among middle-aged women: a cross-sectional analysis of the Nurses' Health Study.GeroScience · 2026Article
- Article
- High-fat diet score reveals total and cardiovascular mortality and identifies protein biomarkers in large cohorts.Journal of advanced research · 2026Article
- Dihydroquercetin Activates AMPK/SIRT1/PGC-1α Signaling to Attenuate Arsenic Trioxide-Induced Apoptosis and Ferroptosis in AC16 Cells and HUVECs.International journal of molecular sciences · 2026Article
- Oxime Functionalization of Naringin and Naringenin: Tuning Structural, Physicochemical, and Biological Profiling.ACS omega · 2026Article
- Therapeutic potential of apigenin in neurodegenerative diseases and brain health.Molecular biology reports · 2026Review
- Enzyme promiscuity-driven co-production of flavonoid 7-Synthetic and systems biotechnology · 2026Article
- Plant-Based Diets, Ultra-Processed Foods, and Risks of Mortality and Major Chronic Diseases: A Prospective Cohort Study.The Lancet regional health. Europe · 2026Article
- Sequential Pyruvic Acid Pretreatment and Alkaline Extraction of Bamboo Leaf Phenolics: Two-Stage Mass Transfer Kinetics.Foods (Basel, Switzerland) · 2026Article
- Article
- Integrated Metabolomics and Selection Signal Analysis Provide Insights Into the Selection for Flavonol Biosynthesis Associated With Lettuce Quality Improvement.Plant biotechnology journal · 2026Article
- BHOD: a bone health optimized dietary pattern designed for osteoporosis prevention.NPJ science of food · 2026Article
- Flavonoid-rich dietary patterns and the risk of incident hearing loss: evidence from the UK Biobank cohort.The journal of nutrition, health & aging · 2026Article
- Animal-Origin Food Waste Across Global Supply Chains: Trends, Upcycling Strategies, and Circular Economy Solutions.Foods (Basel, Switzerland) · 2026Review
- Unveiling the Influence of Polyphenols on Mitogen-activated Protein Kinases in Cancer.Cell biochemistry and biophysics · 2026Review
- The Associations Between Dietary Flavonoid Intake and Neurodegenerative Diseases Risk: A Cross-Sectional Study.Chemical biology & drug design · 2026Article
- Injectable, Conductive, Multifunctional Hydrogels with Sustained Luteolin Release for Promoting Myocardial Infarction Repair.ACS applied materials & interfaces · 2026Article
- Flavonoids.Advances in nutrition (Bethesda, Md.) · 2026Article
- Chemical Constituents Comparison Between the Flowers ofMolecules (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Higher habitual intakes of dietary flavonoids have been linked with a lower risk of all-cause mortality and major chronic disease. Yet, the contribution of diversity of flavonoid intake to health outcomes remains to be investigated. Here, using a cohort of 124,805 UK Biobank participants, we show that participants who consumed the widest diversity of dietary flavonoids, flavonoid-rich foods and/or specific flavonoid subclasses had a 6-20% significantly lower risk of all-cause mortality and incidence of cardiovascular disease, type 2 diabetes, cancer, respiratory disease and neurodegenerative disease. Furthermore, we report that both quantity and diversity of flavonoids are independent predictors of mortality and several chronic diseases, suggesting that consuming a higher quantity and wider diversity is better for longer-term health than either component alone. These findings suggest that consuming several different daily servings of flavonoid-rich foods or beverages, such as tea, berries, apples, oranges or grapes, may lower risk of all-cause mortality and chronic disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.