Evidence map›Paper›PMID 40456505›Full record

ArticleDevelopmental biology2025

Thousands of students gain science research literacy and agency by conducting immersive Drosophila research projects tailored to the health interests of their communities.

Dara M Ruiz Whalen, Carol B Brandt, Alana M O'Reilly

Abstract read
In one paragraph

Article in Developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dara M Ruiz WhalenTemple University, Philadelphia PA, USA; Fox Chase Cancer Center, Philadelphia PA, USA; ECLOSE Institute, Philadelphia, PA, USA. Electronic address: Dara.Whalen@fccc.edu.
Carol B BrandtTemple University, Philadelphia PA, USA.
Alana M O'ReillyFox Chase Cancer Center, Philadelphia PA, USA; ECLOSE Institute, Philadelphia, PA, USA.

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Eric Andrew Ross · 1985 to 2026
$138.8M
Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Mechanisms Controlling Epithelial HomeostasisR01HD065800 · NICHD · RESEARCH INST OF FOX CHASE CAN CTR · PI O'REILLY, ALANA M · 2010 to 2020
$3.9M
Neurotransmitter signaling controls stem cell fateR21HD105295 · NICHD · RESEARCH INST OF FOX CHASE CAN CTR · PI O'REILLY, ALANA M · 2021 to 2022
$514k
NCI NIH HHS P30 CA006927NICHD NIH HHS R01 HD065800NICHD NIH HHS R21 HD105295NIH HHS P40 OD018537
6 · The paper itself

Abstract

Increasing science inquiry that aligns with curriculum standards is emerging as a critical path for science education. Our programming leverages developmental biology to engage students in expansive topics in life sciences that are tailored for each classroom curriculum. These curricula foster a scientific community of practice that prepares today's high school students for future STEM careers. Using developmental stages of the model organism, Drosophila melanogaster, students learn basic laboratory techniques, how to design research trials, write hypotheses, and collect and analyze data. After completing the project, student scientists engage in science communication with professional scientists, peers, and the public at an Annual Research Symposium, solidifying their membership in the scientific community. A core value of the programming is supporting classrooms to design their research to address health concerns of personal importance. This "soul science", an authentic research approach, enables establishment of essential research competencies and prepares students to become health advocates for those they love. This article describes programs designed to increase science inquiry among high school students and their teachers and to encourage the application of experimental outcomes to cancer and disease research.

Indexed as

Developmental BiologyDrosophila melanogasterResearchStudentsAnimalsCurriculumHumansCitizen scienceCommunity health concernsDevelopmental biologyScience research literacyStudent scientists

Identifiers

PMID40456505
PMCPMC12928178

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.