Evidence map›Paper›PMID 40456004›Full record

ArticlePhysical & occupational therapy in pediatrics2025

Efficacy of Hand Arm Bimanual Intensive Therapy in Improving Real-World Bimanual Performance and Identifying Predictors for Therapy Success in Children with Unilateral Cerebral Palsy.

Shailesh S Gardas, Katie Woosley, Caroline Brown, Taylor Key, Natalie McBryde, Brody Morton, Christine Lysaght, Caroline Adams, Holly Holland, Swati M Surkar

Erratum issuedAbstract read
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In one paragraph

Article in Physical & occupational therapy in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Shailesh S GardasDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Katie WoosleyDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Caroline BrownDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Taylor KeyDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Natalie McBrydeDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Brody MortonDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Christine LysaghtDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.
Caroline AdamsDepartment of Occupational Therapy, East Carolina University, Greenville, NC, USA.
Holly HollandOccupational Therapy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Swati M SurkarDepartment of Physical Therapy, East Carolina University, Greenville, NC, USA.

Funding

Remote Ischemic Conditioning to Enhance Motor Learning and Corticospinal Excitability in Children with Unilateral Cerebral PalsyR03HD107644 · NICHD · EAST CAROLINA UNIVERSITY · PI SURKAR, SWATI MANOHARRAO · 2022 to 2023
$327k
NICHD NIH HHS R03 HD107644
6 · The paper itself

Abstract

aimThis study assesses real-world bimanual performance improvements following Hand-Arm Bimanual Intensive Therapy (HABIT) using an objective tool (accelerometers) and to identify demographic and clinical predictors of these gains in children with unilateral cerebral palsy (UCP).

methodsForty children with UCP (mean age: 10.7 ± 3.24 years) participated in 30 h of HABIT. Bilateral wrist-worn accelerometers measured bimanual performance using use ratio, bilateral magnitude, and median acceleration. Self-perceived performance was measured using the Canadian Occupational Performance Measure (COPM), and upper extremity (UE) capacity with Jebsen-Taylor Hand Function Test (JTHFT), Nine-Hole Peg Test (NHPT), and Box and Block Test (BBT). Predictors such as age, sex, affected side, severity levels, and baseline capacity were analyzed.

resultsUse ratio (

conclusionHABIT enhances real-world bimanual performance in children with UCP. Older age and more impaired baseline dexterity are significant predictors of greater therapeutic gains, offering potential strategy to maximize real-world functional gains.

Indexed as

Cerebral PalsyHandOccupational TherapyUpper ExtremityAccelerometryAdolescentChildFemaleHumansMaleTreatment OutcomeAccelerometrybimanual coordinationcerebral palsymotor functionupper extremity

Identifiers

PMID40456004
PMCPMC12323730

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.