Evidence map›Paper›PMID 40455996›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Pathophysiologically relevant bisphenol S exposure accelerates aging by disrupting brown adipose tissue-regulated energy metabolism.

Man Zhu, Ru Wang, Wei Yi, Beiyi Wu, Zhizhong Deng, Zheng Zhang, Chen Wang, Dingkun Zhang, Tongtong Zhang, Xue Wen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Man Zhu *Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0007-4610-105X
Ru Wang *Department of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Wei YiObesity and Metabolism Medicine-Engineering Integration Laboratory, Department of General Surgery, The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, Chengdu 610031, China.ORCID 0009-0003-9046-991X
Beiyi WuDepartment of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.ORCID 0009-0008-3849-6650
Zhizhong DengDepartment of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
Zheng ZhangDepartment of Clinical Laboratory, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.ORCID 0009-0008-2771-3306
Chen WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Soochow University, Suzhou 215006, China.ORCID 0009-0009-0288-9847
Dingkun ZhangDepartment of Clinical Proteomics and Metabolomics, Institutes for Systems Genetics, Frontiers Science Center for Disease-related Molecular Network, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.
Tongtong ZhangObesity and Metabolism Medicine-Engineering Integration Laboratory, Department of General Surgery, The Affiliated Hospital of Southwest Jiaotong University, The Third People's Hospital of Chengdu, Chengdu 610031, China.ORCID 0000-0003-4786-5776
Xue WenDepartment of Plastic and Burn Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) substitutes are widely used as food contact materials and consumer products, while the effects of pathophysiologically relevant concentrations of BPA substitutes on aging remain unclear. In this study, we used

Indexed as

Adipose Tissue, BrownAgingBenzhydryl CompoundsEnergy MetabolismPhenolsSulfonesAnimalsBisphenol S CompoundsCaenorhabditis elegansMaleMiceBenzhydryl Compoundsbisphenol SBisphenol S CompoundsPhenolsSulfonesagingbisphenol Sbrown adipose tissueenergy metabolismhealth span

Identifiers

PMID40455996
PMCPMC12167992

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.