Evidence map›Paper›PMID 40455994›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Symmetries and synchronization from whole-neural activity in the

Bryant Avila, Pedro Augusto, Alireza Hashemi, David Phillips, Tommaso Gili, Manuel Zimmer, Hernán A Makse

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The role of fibration symmetries in geometric deep learning.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  5. Symmetries and synchronization from whole-neural activity in theProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Bryant Avila *Department of Physics and Levich Institute, City College of New York, New York, NY 10031.
Pedro Augusto *Department of Neuroscience and Developmental Biology, University of Vienna, Vienna Biocenter, Vienna 1030, Austria.
Alireza Hashemi *Department of Physics and Levich Institute, City College of New York, New York, NY 10031.ORCID 0000-0002-8491-0102
David PhillipsDepartment of Mechanical Engineering, University of New Mexico, Albuquerque, NM 87131.
Tommaso GiliNetworks Unit, IMT Scuola Alti Studi Lucca, Lucca 55100, Italy.ORCID 0000-0001-9154-1758
Manuel ZimmerDepartment of Neuroscience and Developmental Biology, University of Vienna, Vienna Biocenter, Vienna 1030, Austria.ORCID 0000-0002-8072-787X
Hernán A MakseDepartment of Physics and Levich Institute, City College of New York, New York, NY 10031.ORCID 0000-0001-6474-1324

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Application of the principle of symmetry to neural circuitry: From building blocks to neural synchronization in the connectomeR01EB028157 · NIBIB · CITY COLLEGE OF NEW YORK · PI MAKSE, HERNAN, ZIMMER, MANUEL · 2020 to 2020
$1.1M
DOD | USN | Office of Naval Research (ONR) N00014-22-1-2835NCI NIH HHS P30 CA008748NIBIB NIH HHS R01 EB028157Wellcome Trust
6 · The paper itself

Abstract

Understanding the dynamical behavior of complex systems from their underlying network architectures is a long-standing question in complexity theory. Therefore, many metrics have been devised to extract network features like motifs, centrality, and modularity measures. It has previously been proposed that network symmetries are of particular importance since they are expected to underlie the synchronization of a system's units, which is ubiquitously observed in nervous system activity patterns. However, perfectly symmetrical structures are difficult to assess in noisy measurements of biological systems, like neuronal connectomes. Here, we devise a principled method to infer network symmetries from combined connectome and neuronal activity data. Using nervous system-wide population activity recordings of the

Indexed as

Caenorhabditis elegansConnectomeNerve NetNeuronsAnimalsLocomotionModels, NeurologicalCaenorhabditis eleganscomplex networksconnectomefibration symmetriessynchronization

Identifiers

PMID40455994
PMCPMC12167965

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.