Evidence map›Paper›PMID 40455980›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Structure-function coupling in the first month of life: Associations with age and attention.

Ursula A Tooley, Jeanette K Kenley, M Catalina Camacho, Aidan Latham, Dimitrios Alexopoulos, Ashley N Nielsen, Tara A Smyser, Barbara B Warner, Joshua S Shimony, Jeffrey J Neil and 4 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Structure-function coupling in the first month of life: Associations with age and attention.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ursula A TooleyDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0001-6377-3885
Jeanette K KenleyDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110.
M Catalina CamachoDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0003-0457-5410
Aidan LathamDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110.
Dimitrios AlexopoulosDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0001-5659-8695
Ashley N NielsenDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-7148-8256
Tara A SmyserDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.
Barbara B WarnerDepartment of Pediatrics, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-9910-4461
Joshua S ShimonyDepartment of Radiology, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-6228-776X
Jeffrey J NeilDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-8069-8175
Joan L LubyDepartment of Neurology, Washington University in St. Louis, St. Louis, MO 63110.
Deanna M BarchDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0003-1693-8506
Cynthia E RogersDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.
Christopher D SmyserDepartment of Psychiatry, Washington University in St. Louis, St. Louis, MO 63110.ORCID 0000-0002-4716-5190

Funding

Early Life Adversity, Biological Embedding, and Risk for Developmental Precursors of Mental DisordersR01MH113883 · NIMH · WASHINGTON UNIVERSITY · PI JOAN L. LUBY, Christopher Daniel Smyser · 2018 to 2026
$20.6M
WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
NEUROIMAGING IN EARLY ONSET DEPRESSION: LONGITUDINAL ASSESSMENT OF BRAIN CHANGESR01MH090786 · NIMH · WASHINGTON UNIVERSITY · PI GILBERT, KIRSTEN, WHALEN, DIANA J · 2010 to 2025
$10.4M
Optimizing prediction of preschool psychopathology from brain: behavior markers of emotion dysregulation from birth: A computational, developmental cognitive neuroscience approachR01MH121877 · NIMH · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LUBY, JOAN L., ROGERS, CYNTHIA ELISE · 2020 to 2024
$8.2M
Prenatal Cannabis Use (PCU) and Development of Offspring Brain and Behavior During Early Life (0-18 Months)R01DA046224 · NIDA · WASHINGTON UNIVERSITY · PI ARPANA AGRAWAL, RYAN H BOGDAN · 2019 to 2026
$6.2M
Trajectories of Cortico-Cerebellar Connectivity, Social Competence, and Internalizing Symptoms in Adolescents Born Very PretermR37MH113570 · NIMH · WASHINGTON UNIVERSITY · PI CYNTHIA Elise ROGERS, Christopher Daniel Smyser · 2022 to 2026
$3.8M
THE PRETERM BEHAVIORAL PHENOTYPE: TRAJECTORIES OF PSYCHOPATHOLOGY & CHANGES IN CEREBRAL CONNECTIVITYR01MH113570 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE, SMYSER, CHRISTOPHER DANIEL · 2017 to 2021
$3.1M
Effects of ventricular volume and cerebral connectivity on neurological outcomes in preterm intraventricular hemorrhageR01NS124767 · NINDS · WASHINGTON UNIVERSITY · PI David Delmar Limbrick, Christopher Daniel Smyser · 2022 to 2026
$3.0M
Developmental Pathways to Borderline Personality Disorder: Longitudinal Observational, Clinical, and Neural Predictors From Early Childhood to Young AdulthoodRF1MH090786 · NIMH · WASHINGTON UNIVERSITY · PI Kirsten Gilbert, Diana J Whalen · 2026 to 2026
$1.4M
PREDICTING PRESCHOOL PSYCHOPATHOLOGY WITH BRAIN CONNECTIVITY IN PRETERM NEONATESK23MH105179 · NIMH · WASHINGTON UNIVERSITY · PI ROGERS, CYNTHIA ELISE · 2015 to 2018
$705k
Neonatal predictors of contextualized emotion processing and risk for anxietyF32MH132185 · NIMH · WASHINGTON UNIVERSITY · PI CAMACHO, MARIA CATALINA · 2023 to 2024
$117k
HHS | NIH | National Institute of Mental Health (NIMH) GR0029379HHS | NIH | National Institute of Mental Health (NIMH) MH113570HHS | NIH | National Institute of Mental Health (NIMH) MH113883HHS | NIH | National Institute of Mental Health (NIMH) MH121877HHS | NIH | National Institute of Mental Health (NIMH) MH132185HHS | NIH | National Institute on Drug Abuse (NIDA) DA046224NICHD NIH HHS P50 HD103525NIDA NIH HHS R01 DA046224NIMH NIH HHS F32 MH132185NIMH NIH HHS K23 MH105179NIMH NIH HHS R01 MH090786NIMH NIH HHS R01 MH113570NIMH NIH HHS R01 MH113883NIMH NIH HHS R01 MH121877NIMH NIH HHS R37 MH113570NIMH NIH HHS RF1 MH090786NINDS NIH HHS R01 NS124767WashU | WUSM | Intellectual and Developmental Disabilities Research Center, School of Medicine, Washington University in St. Louis (IDDRC) HD103525WashU | WUSM | Intellectual and Developmental Disabilities Research Center, School of Medicine, Washington University in St. Louis (IDDRC) MH090786WashU | WUSM | Intellectual and Developmental Disabilities Research Center, School of Medicine, Washington University in St. Louis (IDDRC) MH105179
6 · The paper itself

Abstract

How brain structure relates to function is a critical and open question in neuroscience. Here, we characterize regional variation in structure-function coupling, capturing the degree to which a cortical region's structural connections relate to patterns of coordinated neural activity in healthy, term-born neonates (

Indexed as

AttentionBrainAge FactorsBrain MappingFemaleHumansInfantInfant, NewbornMagnetic Resonance ImagingMaleWhite Matterattentionbrain developmentconnectivityinfant

Identifiers

PMID40455980
PMCPMC12168018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.