Evidence map›Paper›PMID 40455713›Full record

ArticlePloS one2025

Guiding ethical principles in transplant candidate selection committees: A scoping review protocol.

Christopher H Kim, Frank G Lee, Tayyab S Diwan, Transplant Ethics Research Lab

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christopher H KimBiomedical Ethics Research Program, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID https://orcid.org/0009-0001-8774-5835
Frank G LeeTransplant Center, Mayo Clinic, Rochester, Minnesota, United States of America.
Tayyab S DiwanTransplant Center, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID https://orcid.org/0000-0002-4153-4469
Transplant Ethics Research Lab

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe goal of this scoping review is to examine the published literature regarding ethical principles that guide solid-organ transplant candidate selection committees. The review will identify the available research and provide recommendations to selection committees.

introductionTransplantation is a field where ethics is involved with almost every juncture of treatment. Organ selection, pathways to donation, organ allocation, and recipient selection are just a few of the myriads of processes that require ethical thoughtfulness. However, the ethical insights involved in the decision-making during these processes are not well elucidated in the literature. An application of an ethical framework(s) to this process could substantially improve the equality of the process. INCLUSION CRITERIA: This review will include studies focused on transplant candidate selection committees and/or the transplant candidate selection process. It will include full papers and abstracts published in English.

methodsPubMED, EMBASE, APA PsycInfo, SCOPUS, and CINAHL databases will be used for the literature search. Only articles published in English between the years 1960 and 2024 will be considered. The review will consist of title/abstract screening followed by full-text screening to determine which articles meet inclusion criteria. Each article will be reviewed by two independent reviewers, with a third stepping in to resolve conflicts in decision. After all articles have been screened, data will be extracted in duplicate from the selected included articles using a template in Covidence created by the study team. Results will then be summarized and presented in narrative summary. DISCUSSION: An examination of the transplant selection process is due and warranted as selection carries significant weight in determining who receives an organ and, indeed, the stakes are life and death. Yet few studies exist on transplant selection. Ultimately, the problem with selection is how committees can further improve their promise to patients: are they making the right decision and how they define "the right decision." Thus, it is critical to review selection committees for systematic bias and discrimination, especially in a process that depends heavily on individuals utilizing judgment-based reasoning, in order to improve selection and rid it of historic biases. This way, the transplant candidate selection process can foster fairness, thereby instilling increased public trust.

Indexed as

Organ TransplantationPatient SelectionTissue and Organ ProcurementDecision MakingHumansScoping Reviews as Topic

Identifiers

PMID40455713
PMCPMC12129203

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.