Evidence map›Paper›PMID 40455561›Full record

ArticleeLife2025

Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of

Hisato Kobayashi, Tatsushi Igaki, Soichiro Kumamoto, Keisuke Tanaka, Tomoya Takashima, So I Nagaoka, Shunsuke Suzuki, Masaaki Hayashi, Marilyn B Renfree, Manabu Kawahara and 12 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Hisato KobayashiDepartment of Embryology, Nara Medical University, Kashihara, Japan.ORCID https://orcid.org/0000-0003-3800-4691
Tatsushi IgakiDepartment of Embryology, Nara Medical University, Kashihara, Japan.
Soichiro KumamotoDepartment of Chemistry and Biochemistry, School of Advanced Science and Engineering, Waseda University, Shinjuku, Japan.ORCID https://orcid.org/0000-0002-3492-117X
Keisuke TanakaDepartment of Informatics, Tokyo University of Information Sciences, Wakaba, Japan.ORCID https://orcid.org/0000-0003-0658-7781
Tomoya TakashimaDepartment of Embryology, Nara Medical University, Kashihara, Japan.ORCID https://orcid.org/0000-0002-3648-1569
So I NagaokaDepartment of Embryology, Nara Medical University, Kashihara, Japan.ORCID https://orcid.org/0000-0002-2377-4936
Shunsuke SuzukiDepartment of Agriculture, Graduate School of Science and Technology, Shinshu University, Nagano, Japan.
Masaaki HayashiDepartment of Agriculture, Graduate School of Science and Technology, Shinshu University, Nagano, Japan.
Marilyn B RenfreeSchool of BioSciences, University of Melbourne, Melbourne, Australia.ORCID https://orcid.org/0000-0002-4589-0436
Manabu KawaharaLaboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.ORCID https://orcid.org/0000-0002-7172-6082
Shun SaitoLaboratory of Animal Genetics and Reproduction, Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.
Toshihiro KobayashiDivision of Mammalian Embryology, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, University of Tokyo, Minato, Japan.ORCID https://orcid.org/0000-0001-8019-0008
Hiroshi NagashimaMeiji University International Institute for Bio-Resource Research, Kawasaki, Japan.
Hitomi MatsunariMeiji University International Institute for Bio-Resource Research, Kawasaki, Japan.
Kazuaki NakanoMeiji University International Institute for Bio-Resource Research, Kawasaki, Japan.ORCID https://orcid.org/0000-0003-1306-6247
Ayuko UchikuraMeiji University International Institute for Bio-Resource Research, Kawasaki, Japan.ORCID https://orcid.org/0000-0002-1535-3808
Hiroshi KiyonariLaboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.ORCID https://orcid.org/0000-0002-1509-8747
Mari KanekoLaboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Kobe, Japan.
Hiroo ImaiMolecular Biology Section, Center for the Evolutionary Origins of Human Behavior, Kyoto University, Inuyama, Japan.ORCID https://orcid.org/0000-0003-0729-0322
Kazuhiko NakabayashiDivision of Developmental Genomics, Research Institute, National Center for Child Health and Development, Setagaya, Japan.ORCID https://orcid.org/0000-0003-2927-0963
Matthew LorinczLife Sciences Institute, Department of Medical Genetics, University of British Columbia, Vancouver, Canada.ORCID https://orcid.org/0000-0003-0885-0467
Kazuki KurimotoDepartment of Embryology, Nara Medical University, Kashihara, Japan.ORCID https://orcid.org/0000-0003-0206-414X

Funding

CIHR PJT-190055Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (A) JP20H00471Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (B) JP21H02382Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (B) JP23K21282Japan Society for the Promotion of Science Grant-in-Aid for Scientific Research (B) JP25K02190Mitsubishi Foundation Grant No. 202310022Takeda Science Foundation 2023 Medical Research Grant Application No. 2023040490
6 · The paper itself

Abstract

The imprinted gene

Indexed as

Genomic ImprintingRetroelementsTerminal Repeat SequencesTranscription, GeneticAnimalsEvolution, MolecularFemaleHumansMiceRabbitsRetroelementschromosomesevolutionary biologygene expressiongenomic imprintinghumanLTR retrotransposonmammalian evolutionmouseplacentarhesus macaqueRNA-seq

Identifiers

PMID40455561
PMCPMC12129452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.