Evidence map›Paper›PMID 40455504›Full record

ArticlePsychology and aging2025

Midlife blues: A lifespan perspective on midlife depressive symptoms.

Tita Gonzalez Avilés, Frank J Infurna, Nutifafa E Y Dey, Yesenia Cruz-Carrillo, Kevin J Grimm, Margie E Lachman, Denis Gerstorf

Abstract read
In one paragraph

Article in Psychology and aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Historical Change in Midlife Development from a Cross-National Perspective.Current directions in psychological science · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tita Gonzalez AvilésDepartment of Psychology, Humboldt University Berlin.ORCID 0000-0001-5267-9439
Frank J InfurnaDepartment of Psychology, Arizona State University.ORCID 0000-0002-0690-9253
Nutifafa E Y DeyDepartment of Psychology, Arizona State University.ORCID 0000-0003-4836-2644
Yesenia Cruz-CarrilloDepartment of Psychology, Arizona State University.ORCID 0009-0008-1288-5535
Kevin J GrimmDepartment of Psychology, Arizona State University.
Margie E LachmanDepartment of Psychology, Brandeis University.ORCID 0000-0003-3027-8735
Denis GerstorfDepartment of Psychology, Humboldt University Berlin.ORCID 0000-0002-2133-9498

Funding

The Mexican Health and Aging Study - IIR01AG018016 · NIA · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Rebeca Wong · 1999 to 2026
$22.6M
Psychosocial Risk and Resilience Mechanisms Underlying Diversity in Midlife Health, Well-Being, and CognitionR01AG079523 · NIA · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI Frank John Infurna · 2022 to 2026
$2.5M
National Institutes of Health; National Institute on AgingNIA NIH HHS R01 AG018016NIA NIH HHS R01 AG079523
6 · The paper itself

Abstract

Midlife is often accompanied by a range of challenges that can heighten the risk of depressive symptoms in middle-aged adults. In this study, we seek to offer a comprehensive understanding of midlife depressive symptoms through a lifespan perspective. Toward that end, we draw on harmonized data from longitudinal studies across 17 nations (the United States, Mexico, China, South Korea, England, and countries in Continental, Mediterranean, and Nordic Europe), comprising a total of 119,534 middle-aged adults (

Indexed as

DepressionAdultEuropeFemaleHumansLongitudinal StudiesMaleMiddle AgedUnited States

Identifiers

PMID40455504
PMCPMC12353782

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.