Evidence map›Paper›PMID 40455341›Full record

ArticleIndian pediatrics2025

Efficacy of Biweekly Iron Supplementation on Iron Status in Under-Five Children: A Prospective Cohort Study.

Krishna Nesara, Dhandapany Gunasekaran, Sharbari Basu

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Article in Indian pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Krishna NesaraJawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Puducherry, 605 006, India.
Dhandapany GunasekaranDepartment of Pediatrics, JIPMER, Puducherry, 605 006, India. drguna007@gmail.com.ORCID 0000-0003-1070-0070
Sharbari BasuDepartment of Biochemistry, JIPMER, Puducherry, 605 006, India.

Funding

Jawaharlal Institute Of Postgraduate Medical Education and Research JIP/Res/Intramural/phs 3/2022-23
6 · The paper itself

Abstract

objectiveTo evaluate the efficacy of prophylactic biweekly Iron and Folic acid (IFA) supplementation (National Iron Plus Initiative) in maintaining iron status in under-five children with iron sufficiency.

methodsConsecutive healthy children screened for normal iron status (normal hemoglobin and serum ferritin) were started on iron prophylaxis as one mL syrup containing 20 mg elemental iron and 100 µg folic acid biweekly for six months. The pre- and post-supplementation hemoglobin and serum ferritin levels were compared.

resultsOut of 573 children screened, none were receiving IFA prophylaxis routinely. A total of 173 out of 200 eligible children completed the intervention with a significant increase in the mean (SD) hemoglobin [11.7 (0.5)-11.9 (0.5) g/dL] and serum ferritin [54.5 (23.5)- 63.6 (21.1) µg/L] at six months (P < 0.001).

conclusionsBiweekly iron and folic acid supplementation improved iron status in children aged 1 to 5 years with iron sufficiency.

Indexed as

Anemia, Iron-DeficiencyDietary SupplementsFolic AcidIronChild, PreschoolFemaleFerritinsHemoglobinsHumansInfantMaleProspective StudiesFerritinsFolic AcidHemoglobinsIronAnemia Mukt BharatIron supplementationNational iron plus initiativeNutritional anemiaPreschool children

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.