Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
A home-based 12-week chair exercise intervention for older adults with advanced cancer receiving chemotherapy: a randomized pilot feasibility trial.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
Abstract
purposeOlder adults with advanced cancer are at risk for toxicities and declines in physical function, which can impact their ability to perform instrumental activities of daily living (IADLs, e.g., preparing meals, managing medications, and cleaning). This decline is a key predictor of treatment outcomes and survival in this population. To address this, we conducted a two-arm, randomized trial to evaluate the feasibility of a home-based chair exercise intervention (ChairEx), delivered in-clinic by oncology staff.
methodsOlder adults (n = 27; mean age: 74 years; 62% female; 67% White) with advanced cancer receiving chemotherapy were recruited from community oncology clinics and randomized to ChairEx (5 days/week, rate of perceived exertion [RPE] of 3-5 light-moderate intensity, 30 min/day, seated strengthening and stretching exercises), or usual care (UC). Adherence was tracked with exercise diaries. IADLs were assessed via OARS-IADL.
resultsAmong 34 screened, 27 (79%) were eligible, consented, and randomized. Seventy-eight percent (21/27) completed all study visits. ChairEx participants exercised a median of 5 days/week for 22 min/day at an RPE of 3.3, with no adverse events. Oncology staff found ChairEx minimally disruptive to clinic workflow. All ChairEx participants recommended the intervention. ChairEx participants reported improvements in IADLs (Cohen's d = 0.52), compared to UC (p = 0.026). Non-significant improvements in physical function, fatigue, and depression were observed.
conclusionChairEx was safe, feasible, and well received by older patients with advanced cancer receiving chemotherapy. Results suggest that ChairEx may improve IADLs, physical function, fatigue, and depression. Phase II randomized clinical trials are warranted to confirm these findings.
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