ArticleDiscover oncology2025
Hotspots and frontiers of extracellular vesicles and lung cancer: a bibliometric and visualization analysis from 2002 to 2024.
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Global trends and future directions in COVID-19 and leukemia research from 2020 to 2024.Discover oncology · 2025Article
- Extracellular vesicles derived from Schwann cells to enhance bone and dental tissue regeneration: a literature review.Journal of nanobiotechnology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeExtracellular vesicles (EVs) play a crucial role in promoting tumor progression in lung cancer (LC) and serve as potential diagnostic and therapeutic targets. Despite their significance, no comprehensive bibliometric analysis of global research on EVs and LC has been conducted. This analysis aims to address this gap by highlighting key trends, contributors, and future directions.
methodsA total of 1,002 publications from 2002 to 2024 were extracted from the Web of Science Core Collection. The analysis was conducted using VOSviewer, CiteSpace, and the R package "Bibliometrix".
resultsThe study includes contributions from 6337 researchers across 1339 institutions in 60 countries, with findings published in 404 journals. The number of publications has steadily increased, with China and the United States leading the output, and Nanjing Medical University being the largest contributor. Cancer published the most articles, while Cancer Research had the highest number of co-citations. Jing Li was the most productive author, and C. Thamesry was the most frequently co-cited. Major research themes included "the pro-metastatic role of exosomal miRNAs", "liquid biopsy diagnostics", "aptamer-binding proteomics diagnosis", "macrophage regulation by autophagy and hypoxia", "anti-cancer effects of exosomes", "nanomedicine delivery and immunotherapy", "non-coding RNA markers", and "immune regulation of the tumor microenvironment". Future studies are expected to focus on "emerging diagnostic biomarkers", "tumor microenvironment regulation", and "nanomedicine delivery".
conclusionThis is the first bibliometric analysis on EVs and LC, providing an overview of global research trends and emerging therapeutic strategies. The findings provide valuable insights for future investigations and treatment optimization.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.