ReviewCurrent microbiology2025
Investigating c-di-GMP Signaling in Vibrio parahaemolyticus: Biological Effects and Mechanisms of Regulation.
Review in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- Strain-level heterogeneity in Vibrio parahaemolyticus limits the predictive value of baseline planktonic gene expression for surface-associated phenotypes.Scientific reports · 2026Article
- Transposon mutant library reveals the complex regulatory network of biofilm formation inBiofilm · 2026Article
- Antimicrobial and anti-biofilm activity of Epigallocatechin gallate against Vibrio parahaemolyticus.NPJ science of food · 2026Article
- Functional divergence and regulatory network of the type VI secretion system inJournal of bacteriology · 2026Review
- LtrB inhibitsCurrent research in food science · 2026Article
- Sodium taurocholate induces a colonization-adapted state in Vibrio parahaemolyticus by repressing acute virulence and promoting adhesion.BMC microbiology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Vibrio parahaemolyticus is a halophilic, Gram-negative bacterium found in marine and estuarine ecosystems and is a significant contributor to seafood-related bacterial gastroenteritis. Cyclic di-GMP (c-di-GMP) is a widespread secondary messenger that modulates various cellular pathways, including virulence factor production, motility, and biofilm formation. c-di-GMP is made by diguanylate cyclases (DGCs), while its breakdown is mediated by phosphodiesterases (PDEs). Although many putative DGCs and PDEs involved in c-di-GMP metabolism have been identified in V. parahaemolyticus, only a few have been thoroughly studied. Furthermore, the metabolism of c-di-GMP is influenced by various environmental factors and transcriptional regulators. This review provides an overview of the c-di-GMP signaling network in V. parahaemolyticus, focusing on recent advancements related to c-di-GMP metabolic enzyme genes and their regulatory mechanisms. Understanding the intricate mechanisms of c-di-GMP metabolism and regulation is crucial for revealing the environmental adaptation and pathogenic strategies of V. parahaemolyticus.
Indexed as
Identifiers
40455311What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.