Evidence map›Paper›PMID 40455278›Full record

ArticleMolecular biology reports2025

Impact of Ilex paraguariensis extract on osteoblastic phenotype expression.

Antônio Secco Martorano, Walter Raucci Neto, Lucas Novaes Teixeira, Carolina Martinelli Bordignon, Paulo Tambasco de Oliveira, Larissa Moreira Spinola de Castro Raucci

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Celastrol Attenuates FGF23 Expression in Osteoblasts by Inhibiting STAT3 Activation.Endocrine, metabolic & immune disorders drug targets · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antônio Secco MartoranoSchool of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo, SP, Brazil. antoniomartora@gmail.com.ORCID https://orcid.org/0000-0002-7034-9772
Walter Raucci NetoSchool of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo, SP, Brazil.
Lucas Novaes TeixeiraCell Biology and Oral Pathology Division - Faculdade São Leopoldo Mandic, Campinas, SP, Brazil.
Carolina Martinelli BordignonFaculty of Dentistry, University of Ribeirão Preto, Ribeirão Preto, SP, Brazil.
Paulo Tambasco de OliveiraSchool of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo, SP, Brazil.
Larissa Moreira Spinola de Castro RaucciFaculty of Dentistry, University of Ribeirão Preto, Ribeirão Preto, SP, Brazil.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 88882.365158/2019-01
6 · The paper itself

Abstract

backgroundThe use of dietary supplements and the functionalization of biomaterials with natural compounds have been explored to enhance bone regeneration. While Ilex paraguariensis St. Hil (yerba mate) has shown benefits in various tissues, its effects on bone tissue remain underexplored. This study evaluated the impact of Ilox METHODS AND

resultsTo this end, osteoblasts from the UMR-106 cell line were exposed to 0 (control), 10, 30, and 60 µg/mL of lyophilized Ilox

conclusionBased on the obtained results, it can be concluded that Ilox

Indexed as

Ilex paraguariensisOsteoblastsPlant ExtractsAlkaline PhosphataseAnimalsAntioxidantsCell DifferentiationCell LineCell SurvivalOsteogenesisPhenotypeAlkaline PhosphataseAntioxidantsPlant Extracts

Identifiers

PMID40455278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.