ArticleEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025
Leukopenia and leukocytosis are associated with early postoperative complications following aseptic revision total shoulder arthroplasty.
Article in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- A Retrospective Review of Antimicrobial Usage and Indications at End-of-Life for Oncology Patients in a Tertiary Cancer Center in Saudi Arabia.Saudi medical journal · 2026Article
- 30-Day Readmission Following Inpatient Total Shoulder Arthroplasty in Pennsylvania: A Statewide Analysis.JB & JS open accessArticle
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5 authors.
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Abstract
backgroundThis study investigates the association between preoperative leukopenia and leukocytosis with 30-day postoperative complications following noninfectious revision total shoulder arthroplasty (TSA).
methodsThe American College of Surgeons National Surgical Quality Improvement Program database was queried for all patients who underwent noninfectious revision TSA from 2015 to 2022. The study population was divided into three groups based on preoperative white blood cell (WBC) count: normal (WBC 4500-11,000), leukopenia (WBC ≤ 4500), and leukocytosis (WBC ≥ 11,000). Logistic regression analysis was conducted to investigate the relationship between WBC count and postoperative complications.
resultsCompared to normal WBC counts, leukocytosis was independently associated with an increased likelihood of experiencing any complication (OR 1.71, 95% CI 1.13-2.59; P = 0.012), sepsis (OR 5.31, 95% CI 1.38-20.37; P = 0.015), non-home discharge (OR 2.18, 95% CI 1.18-4.05; P = 0.013), readmission (OR 2.76, 95% CI 1.36-5.63; P = 0.005), and LOS > 2 days (OR 1.68, 95% CI 1.06-2.66; P = 0.028). Compared to normal WBC counts, leukopenia was independently associated with an increased likelihood of experiencing pneumonia (OR 14.98, 95% CI 2.32-96.56; P = 0.004) and readmission (OR 2.78, 95% CI 1.49-5.17; P = 0.001).
conclusionThe present study identified preoperative leukocytosis and leukopenia as independent risk factors for 30-day postoperative complications following revision TSA. Integrating WBC count into preoperative assessments can enhance the identification of patients at risk for postoperative complications, allowing for more tailored management strategies and potentially improving overall patient outcomes.
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