Evidence map›Paper›PMID 40455252›Full record

ArticleArchives of orthopaedic and trauma surgery2025

Increased risk of deep vein thrombosis and surgical site infection in cemented total knee arthroplasty: A nationwide propensity score-matched study in Japan.

Yu Mori, Kunio Tarasawa, Hidetatsu Tanaka, Masayuki Kamimura, Kento Harada, Naoko Mori, Kiyohide Fushimi, Toshimi Aizawa, Kenji Fujimori

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Article in Archives of orthopaedic and trauma surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yu MoriDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan. yu.mori.c4@tohoku.ac.jp.
Kunio TarasawaDepartment of Health Administration and Policy, Tohoku University Graduate School of Medicine, Sendai, Japan.
Hidetatsu TanakaDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Masayuki KamimuraDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kento HaradaDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Naoko MoriDepartment of Radiology, Akita University Graduate School of Medicine, Akita, Japan.
Kiyohide FushimiDepartment of Health Policy and Informatics, Institute of Science Tokyo, Tokyo, Japan.
Toshimi AizawaDepartment of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kenji FujimoriDepartment of Health Administration and Policy, Tohoku University Graduate School of Medicine, Sendai, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionTotal knee arthroplasty (TKA) is a widely used treatment for advanced knee osteoarthritis. While cemented fixation is the standard technique, cementless fixation has demonstrated comparable long-term outcomes. However, the association between cement use and postoperative complications, including venous thromboembolism and surgical site infections, remains unclear, particularly in Japanese patients. This study aimed to investigate the incidence of postoperative complications in cemented and cementless TKA using a nationwide database.

methodsA nationwide cohort study was conducted using Japan's DPC database from April 2016 to March 2023. Patients who underwent TKA were identified, and postoperative complications, including deep vein thrombosis, pulmonary embolism, pneumonia, cerebrovascular events, postoperative cognitive dysfunction, and surgical site infection, were analyzed. One-to-one propensity score (PS) matching was performed based on age, sex, body mass index, type of anesthesia, simultaneous bilateral surgery, Charlson comorbidity index, and comorbidities to ensure comparability. Statistical analyses included χ² tests, Student's t-tests, and multivariate logistic regression analysis.

resultsA total of 228,595 patients met the eligibility criteria, with 21,906 matched pairs in the cemented and cementless groups after PS matching. The incidence of deep vein thrombosis (OR: 1.231, 95% CI: 1.151-1.316, p < 0.0001) and surgical site infection (OR: 1.716, 95% CI: 1.420-2.073, p < 0.0001) was significantly higher in the cemented group. No significant differences were observed in pulmonary embolism or other complications.

conclusionCement application was associated with an increased risk of deep vein thrombosis and surgical site infection. These findings suggest that careful perioperative management may be warranted in patients undergoing cemented TKA.

Indexed as

Arthroplasty, Replacement, KneeBone CementsSurgical Wound InfectionVenous ThrombosisAgedAged, 80 and overFemaleHumansIncidenceJapanMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRisk FactorsBone CementsBone cementComplicationNationwide databasePropensity score matchingTotal knee arthroplasty

Identifiers

PMID40455252
PMCPMC12130105

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.