Evidence map›Paper›PMID 40455247›Full record

ArticlePlant cell reports2025

Sucrose transport gene FaSWEET9a regulated by FaDOF2 transcription factor promotes sucrose accumulation in strawberry.

Yan Xu, Shuang Liu, Hongying Sun, Jian Zang, Chao Zhang, Wei Guo, Zhihong Zhang

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Article in Plant cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yan XuLiaoning Key Laboratory of Strawberry Breeding and Cultivation, College of Horticulture, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.
Shuang LiuLiaoning Key Laboratory of Strawberry Breeding and Cultivation, College of Horticulture, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.
Hongying SunLiaoning Key Laboratory of Strawberry Breeding and Cultivation, College of Horticulture, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.
Jian ZangAnalytical and Testing Center, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.
Chao ZhangLiaoning Key Laboratory of Strawberry Breeding and Cultivation, College of Horticulture, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China.
Wei GuoLiaoning Key Laboratory of Strawberry Breeding and Cultivation, College of Horticulture, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China. guowei0824@syau.edu.cn.
Zhihong ZhangLiaoning Key Laboratory of Strawberry Breeding and Cultivation, College of Horticulture, Shenyang Agricultural University, 120 Dongling Road, Shenyang, 110866, China. zhangz@syau.edu.cn.ORCID http://orcid.org/0000-0001-5935-1567

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 32130092Liaoning Province Germplasm Innovation Grain Storage and Technology Special Program 2023020525-JH1/102-04
6 · The paper itself

Abstract

key messageFaSWEET9a, an important sucrose transport gene regulated by transcription factor FaDOF2, regulates the accumulation of sucrose in strawberry fruits and affects the growth of strawberry plants.. This study identified and characterized 25 members of the SWEET gene family in the genome of cultivated strawberry (Fragaria × ananassa cv. 'Yanli'), focusing on their potential roles in fruit development. Notably, FaSWEET9a, a specific member of the SWEET family, was found to be uniquely expressed in 'Yanli' fruit. Functional analysis via heterologous expression in Saccharomyces cerevisiae confirmed that FaSWEET9a acts as a sucrose transporter. To further investigate its role, we generated FaSWEET9a overexpression lines and demonstrated that FaSWEET9a not only enhances sucrose accumulation in strawberry fruits but also influences plant growth and development. We identified FaDOF2 that could bind to the promoter of FaSWEET9a and enhance its transcription by conducting yeast one-hybrid assays, electrophoretic mobility shift assays, β-glucuronidase assays, and luciferase reporter gene assays. Moreover, transient transformation experiments revealed that FaDOF2 could elevate sucrose content in strawberry fruits by regulating FaSWEET9a. This research brings new viewpoints on the molecular mechanisms that govern sucrose regulation in strawberry fruits, spotlighting the functional significance of the FaSWEET9a-FaDOF2 regulatory module in the aspects of fruit quality and development.

Indexed as

FragariaPlant ProteinsSucroseTranscription FactorsFruitGene Expression Regulation, PlantMembrane Transport ProteinsPlants, Genetically ModifiedPromoter Regions, GeneticSaccharomyces cerevisiaeMembrane Transport ProteinsPlant ProteinsSucrosesucrose transport protein, plantTranscription FactorsFaDOF2FaSWEET9aFruit sweetnessGene regulationSucrose transport

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.