Evidence map›Paper›PMID 40455057›Full record

ArticleDevelopmental cognitive neuroscience2025

Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach.

Kelly K Gurka, Heather H Burris, Lucia Ciciolla, Claire D Coles, Suena H Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M Smith, Anna Zilverstand, Gretchen Bandoli and 1 more

Abstract readMulticenter Study
In one paragraph

Article in Developmental cognitive neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kelly K GurkaUniversity of Florida, PO Box 100231, Gainesville, FL 32610-0231, USA. Electronic address: kgurka@virginia.edu.
Heather H BurrisChildren's Hospital of Philadelphia, University of Pennsylvania, 734 Schuylkill Ave, Room 19363, Philadelphia, PA 19146, USA. Electronic address: burrish@chop.edu.
Lucia CiciollaOklahoma State University, 116 Psychology Building, Stillwater, OK 74074, USA. Electronic address: lucia.ciciolla@okstate.edu.
Claire D ColesEmory University School of Medicine, 12 Executive Park Drive, Atlanta, GA 30329, USA. Electronic address: ccoles@emory.edu.
Suena H MasseyMassachusetts General Hosptial, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: smassey1@mgh.harvard.edu.
Sharlene NewmanUniversity of Alabama, NE Medical Building, Box 870328, Tuscaloosa, AL 35487, USA. Electronic address: sdnewman@ua.edu.
Vidya RajagopalanChildren's Hospital Los Angeles, Keck School of Medicine, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA 90703, USA. Electronic address: vrajagopalan@chla.usc.edu.
Lynne M SmithHarbor-UCLA Medical Center, 1124 West Carson Street, Box 17, Torrance, CA 90502, USA. Electronic address: smith@lundquist.org.
Anna ZilverstandUniversity of Minnesota, 717 Delaware Street, Minneapolis, MN 55414, USA. Electronic address: annaz@umn.edu.
Gretchen BandoliUniversity of California San Diego, 9500 Gilman Drive, MC 0828, La Jolla, CA 92093, USA. Electronic address: gbandoli@health.ucsd.edu.
HBCD Pregnancy Exposures, Including Substances Workgroup

Funding

The Healthy Brain and Child Development National Consortium Administrative CoreU24DA055325 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHRISTINA CHAMBERS, CHARLES Alexander NELSON · 2021 to 2026
$40.8M
Healthy Brain and Child Development National Consortium Data Coordinating CenterU24DA055330 · NIDA · WASHINGTON UNIVERSITY · PI ANDERS M DALE, Damien A Fair · 2021 to 2026
$34.6M
5/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) ConsortiumU01DA055344 · NIDA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Stephanie Engel, Weili Lin · 2021 to 2026
$13.9M
6/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) Consortium VanderbiltU01DA055347 · NIDA · VANDERBILT UNIVERSITY · PI Laurie E Cutting, Sarah Scheiderich Osmundson · 2021 to 2026
$12.7M
4/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) ConsortiumU01DA055342 · NIDA · CINCINNATI CHILDRENS HOSP MED CTR · PI STEPHANIE L MERHAR, JENNIFER J. VANNEST · 2021 to 2026
$11.9M
1/6 HBCD Prenatal Experiences and Longitudinal Development (PRELUDE) ConsortiumU01DA055352 · NIDA · ARKANSAS CHILDREN'S HOSPITAL RES INST · PI ASHLEY ACHESON, LORRAINE M MCKELVEY · 2021 to 2026
$11.9M
HEALthy Brain and Child Development Study at UAB and UAU01DA055322 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Rajesh K Kana, Cassandra R. Newsom · 2021 to 2026
$11.2M
23/24 Healthy Brain and Child Development National ConsortiumU01DA055367 · NIDA · WASHINGTON UNIVERSITY · PI RYAN H BOGDAN, CYNTHIA Elise ROGERS · 2021 to 2026
$10.8M
7/24 Healthy Brain and Child Development National ConsortiumU01DA055350 · NIDA · JOHNS HOPKINS UNIVERSITY · PI JAMES J. PEKAR, ANDREW J. SATIN · 2021 to 2026
$10.7M
2/24 Healthy Brain and Child Development National ConsortiumU01DA055362 · NIDA · CHILDREN'S HOSPITAL OF LOS ANGELES · PI PAT LEVITT, Beth A Smith · 2021 to 2026
$9.6M
16/24 Healthy Brain and Child Development National Consortium HEAL Diversity SupplementU01DA055316 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI Nathan A Fox, Brenda J Harden · 2021 to 2026
$9.5M
8/24 The Healthy Brain and Child Development National ConsortiumU01DA055338 · NIDA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Obianuju Berry, Lauren Christine Shuffrey · 2021 to 2026
$9.4M
NIDA NIH HHS U01 DA055316NIDA NIH HHS U01 DA055322NIDA NIH HHS U01 DA055338NIDA NIH HHS U01 DA055342NIDA NIH HHS U01 DA055344NIDA NIH HHS U01 DA055347NIDA NIH HHS U01 DA055350NIDA NIH HHS U01 DA055352NIDA NIH HHS U01 DA055354NIDA NIH HHS U01 DA055355NIDA NIH HHS U01 DA055357NIDA NIH HHS U01 DA055358NIDA NIH HHS U01 DA055359NIDA NIH HHS U01 DA055360NIDA NIH HHS U01 DA055361NIDA NIH HHS U01 DA055362NIDA NIH HHS U01 DA055363NIDA NIH HHS U01 DA055366NIDA NIH HHS U01 DA055367NIDA NIH HHS U01 DA055370NIDA NIH HHS U24 DA055325NIDA NIH HHS U24 DA055330
6 · The paper itself

Abstract

The Healthy Brain and Child Development (HBCD) Study, a multi-site, prospective, longitudinal cohort study, will examine human brain, cognitive, behavioral, social, and emotional development beginning prenatally and planned through early childhood. Prenatal exposures, including substances of abuse, impact fetal development and have effects across the life course. During the development of the HBCD Study, the Pregnancy Exposures, Including Substances Workgroup (WG-PRG) was charged with characterizing maternal health and behavior during pregnancy into the childhood years. Maternal physical and mental health, including substance use, and pregnancy and birth complications and outcomes were prioritized. Pregnancy, chronic and acute health conditions, family mental health, and healthcare utilization were assessed using existing and novel measures. Maternal mental health was assessed with the Edinburgh Postpartum Depression Scale, select items in the DSM-5 Self-Rated Level-1 and -2 Cross-Cutting Symptom Measures, and the National Stressful Events Survey-PTSD Short Scale. Finally, participants reported lifetime, recent, and current use of substances using a modified-ASSIST during pregnancy and postpartum. Quantities and frequencies of reported substances were collected for select periods prior to and during pregnancy through an interview (or web application) using the timeline-followback method. HBCD will advance our understanding of the impact of the intrauterine environment on early development.

Indexed as

BrainChild DevelopmentMaternal HealthPregnancy ComplicationsPrenatal Exposure Delayed EffectsAdultChildChild, PreschoolFemaleHumansLongitudinal StudiesMental HealthPregnancyProspective StudiesSubstance-Related DisordersYoung AdultBrainChild developmentHBCDMaternal healthPregnancyPrenatal exposure delayed effectsSubstance-related disorders

Identifiers

PMID40455057
PMCPMC11743802

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.