Evidence map›Paper›PMID 40455054›Full record

ArticleInterdisciplinary cardiovascular and thoracic surgery2025

Ascending aortic aneurysm and dissection risk: focus on aortic height index.

Susanna Grego, Alberto Pozzoli, Tiziano Torre, Laura Anna Leo, Mirko Muretti, Francesca Toto, Thomas Theologou, Enrico Ferrari, Stefanos Demertzis

Abstract read
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Article in Interdisciplinary cardiovascular and thoracic surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Susanna GregoRare Cardiovascular Disease Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Alberto PozzoliHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.ORCID 0000-0002-1184-7210
Tiziano TorreHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Laura Anna LeoCardiovascular Imaging & Cardiology Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Mirko MurettiHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Francesca TotoHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Thomas TheologouHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.ORCID 0000-0002-0255-5814
Enrico FerrariHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.
Stefanos DemertzisHeart Surgery Unit, Cardiocentro Ticino Institute, EOC, Lugano, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAcute aortic dissection (AAD) commonly occurs with a dilation of the ascending aorta at diameters under the threshold of surgical indication. Aortic diameter/height index (AHI) has been proposed for risk stratification and more accurate prophylactic surgery.

methodsFrom January 2001 to November 2023, all patients operated on for AAD at our Institute were prospectively collected and retrospectively analysed, calculating the AHI. A Control Group without aortic pathology was stratified for the same risk index, and a modelling risk analysis for aortic dissection was also performed.

resultsA group of 210 patients was operated during the study period, of whom 168 (80%) had a prevalent post-junctional aortic dilation with a mean aortic diameter at the time of diagnosis of 5.1 ± 0.7 cm. In 53/210 (25%), the aortic diameter was > 5.5 cm. According to AHI, 19/210 patients (9%) were low-risk, 142/210 (67.6%) moderate, 45/210 (21.3%) high and 4/210 (2%) severe risk. In the AHI probability density function, the peak for dissection was 2.93 cm/m for males and 3.05 for females. Control were 6343 patients (3.2% at moderate risk) with AHI of 2.01 cm/m. After simulating the dissecting process, 215 (3.3%) had AHI ≥ 2.9 cm/m.

conclusionsThe measurement of the aortic diameter to height index in patients with acute aortic dissection revealed a significant prevalence of individuals presenting a moderate risk for acute aortic events. Regardless of absolute aortic diameter values, patients with AHI exceeding 2.9 cm/m should be referred to an aortic centre for multidisciplinary risk assessment.

Indexed as

AortaAortic AneurysmAortic DissectionAdultAgedAneurysm, Ascending AortaBody HeightFemaleHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk Factorsacute aortic dissection riskaortic diameter/height indexascending aorta aneurysmprevention

Identifiers

PMID40455054
PMCPMC12187048

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