Evidence map›Paper›PMID 40454848›Full record

ArticleMicrobiology spectrum2025

Comprehensive biological evaluation of infuzide as a potent antimicrobial, alone and in combination with gentamicin, linezolid, and minocycline targeting MDR

Rahul Maitra, Deepanshi Saxena, Abdul Akhir, Anna Kapusterynska, Michel Baltas, Sidharth Chopra

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rahul MaitraDivision of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Deepanshi Saxena *Division of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Abdul Akhir *Division of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.
Anna KapusterynskaCNRS, Laboratoire de Chimie de Coordination (LCC) Inserm ERL 1289, Université de Toulouse, UPS, INPT, Toulouse, Occitanie, France.
Michel BaltasCNRS, Laboratoire de Chimie de Coordination (LCC) Inserm ERL 1289, Université de Toulouse, UPS, INPT, Toulouse, Occitanie, France.ORCID 0000-0002-8785-7095
Sidharth ChopraDivision of Molecular Microbiology and Immunology, CSIR-Central Drug Research Institute, Lucknow, Uttar Pradesh, India.ORCID 0000-0001-8823-6074

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antimicrobial resistance is the greatest threat to modern healthcare systems. The unrelentingly increasing drug resistance manifests in ESKAPE pathogens, thus necessitating urgent novel drug discovery. Whole cell-screening assays were used to identify Infuzide, expressing potent antimicrobial activity against gram-positive pathogens

Indexed as

Anti-Bacterial AgentsEnterococcusStaphylococcus aureusAnimalsBiofilmsDisease Models, AnimalDrug Resistance, Multiple, BacterialDrug SynergismFemaleGentamicinsHumansLinezolidMiceMicrobial Sensitivity TestsMinocyclineStaphylococcal InfectionsAnti-Bacterial AgentsGentamicinsLinezolidMinocyclineantimicrobial agentsmechanochemicalStaphylococcus aureus

Identifiers

PMID40454848
PMCPMC12211062

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.