Evidence map›Paper›PMID 40454839›Full record

ArticleJournal of clinical microbiology2025

Performance of the LIAISON PLEX yeast blood culture assay for identifying 16 invasive fungal pathogens in blood cultures.

Christopher L Emery, Neelam Dhiman, Siu-Kei Chow, Gwyn Peterson, Paul Granato, Brian Bernier, Janet Farhang

Abstract readMulticenter StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. UnmaskingPathogens (Basel, Switzerland) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christopher L EmeryIndiana University Health, Indianapolis, Indiana, USA.ORCID 0000-0002-2793-073X
Neelam DhimanQuest Diagnostics, Lewisville, Texas, USA.
Siu-Kei ChowMultiCare Health System, Tacoma, Washington, USA.ORCID 0000-0003-4178-3307
Gwyn PetersonMultiCare Health System, Tacoma, Washington, USA.
Paul GranatoLaboratory Alliance of Central New York, Liverpool, New York, USA.ORCID 0000-0002-5068-1137
Brian BernierLuminex Corporation, Austin, Texas, USA.
Janet FarhangLuminex Corporation, Austin, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fungi frequently cause potentially life-threatening bloodstream infections, particularly in immunocompromised and hospitalized individuals. Molecular methods can allow earlier pathogen identification for faster optimization of appropriate therapy. This multisite study evaluated the analytical and clinical performance of the automated multiplex LIAISON PLEX Yeast Blood Culture nucleic acid assay (Luminex Corporation, Northbrook, IL), which detects and identifies 14 IMPORTANCE: Bloodstream fungal infections have serious risks of illness and death. Optimal treatment requires early pathogen identification so appropriate antifungal therapy can be immediately started. Blood culture is standard for confirming fungal infection but takes several days for results and may not provide detailed pathogen information. The LIAISON PLEX Yeast Blood Culture assay quickly analyzes fungus-positive blood cultures to identify 16 pathogenic fungi, including multiple

Indexed as

Blood CultureFungiInvasive Fungal InfectionsMolecular Diagnostic TechniquesCandidaCryptococcusHumansProspective StudiesReproducibility of ResultsSensitivity and Specificityblood cultureCandidaCryptococcusin vitro diagnostic assaymolecular syndromic panelsample-to-answer

Identifiers

PMID40454839
PMCPMC12239718

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.