Evidence map›Paper›PMID 40454770›Full record

Trial reportClinical cardiology2025

Effectiveness of Cardiac Rehabilitation in Enhancing Adherence and Improving Clinical Outcomes Post-Acute Coronary Syndrome: A Randomized Controlled Trial.

Haşim Tüner, Fuat Polat, Enes Alıç, Ali Nail Kaya, Çiğdem Bahar Çakmak, Ferhat Coşkun, Emrah Özbek

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haşim TünerDepartment of Cardiology, Istanbul Arel University Memorial Bahcelievler Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0003-2356-1460
Fuat PolatDepartment of Cardiology, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Educatıon Research Hospıtal, İstanbul, Türkiye.ORCID https://orcid.org/0000-0002-6414-3743
Enes AlıçDepartment of Cardiology, Istanbul Aydin University VM Medical Park Florya Hospital, İstanbul, Türkiye.ORCID https://orcid.org/0000-0003-0517-6243
Ali Nail KayaDepartment of Cardiology, Hakkari State Hospital, Hakkari, Türkiye.ORCID https://orcid.org/0000-0003-0917-6144
Çiğdem Bahar ÇakmakDepartment of Cardiology, Samsun Gazi State Hospital, Samsun, Türkiye.ORCID https://orcid.org/0000-0001-5337-5226
Ferhat CoşkunDepartment of Cardiology, Batman Health Sciences University Training and Research Hospital, Batman, Türkiye.ORCID https://orcid.org/0000-0003-4873-273X
Emrah ÖzbekDepartment of Cardiology, Van Health Sciences University Training and Research Hospital, Van, Türkiye.ORCID https://orcid.org/0000-0003-0724-6700

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

backgroundAcute coronary syndrome (ACS) remains a major contributor to cardiovascular morbidity and mortality. Cardiac rehabilitation programs have shown promise in improving adherence to lifestyle and medical recommendations, yet their impact on clinical outcomes and complications requires further investigation.

methodsThis prospective, randomized, single-center study evaluated the effects of cardiac rehabilitation on adherence and clinical outcomes in ACS patients. A total of 340 patients were randomized into a Cardiac Rehabilitation Group or Control Group. The Cardiac Rehabilitation Group underwent supervised exercise, dietary counseling, and education, while the Control Group received standard recommendations. Outcomes, including adherence rates and complications, were assessed over 1 year, with additional interim analyses to evaluate early sustainability of behavioral changes.

resultsPatients in the Cardiac Rehabilitation Group demonstrated significant improvements in adherence to dietary recommendations (73.5% vs. 52.4%, p < 0.01) and physical activity (85.3% vs. 68.2%, p < 0.01). Cardiac Rehabilitation Group patients also experienced fewer instances of weight gain (22.9% vs. 34.7%, p = 0.017) and access site complications (21.2% vs. 40%, p < 0.01). Hospital readmissions were reduced in the Cardiac Rehabilitation Group compared to the Control Group (18.8% vs. 31.2%, p = 0.015). Non-adherence to dietary recommendations (HR: 2.42, 95% CI: 1.08-5.41, p = 0.032) and medical treatments (HR: 2.84, 95% CI: 1.32-6.11, p = 0.007) were significantly associated with increased risk of revascularization.

conclusionCardiac rehabilitation significantly enhances adherence to medical and lifestyle recommendations, reduces complications, and improves outcomes in ACS patients. These findings emphasize the critical role of structured rehabilitation in post-ACS management.

Indexed as

Acute Coronary SyndromeCardiac RehabilitationExercise TherapyPatient ComplianceRisk Reduction BehaviorAgedExerciseFemaleHumansMaleMiddle AgedPatient Education as TopicPatient ReadmissionProspective StudiesRisk FactorsTime Factorsacute coronary syndromeadherencecardiac rehabilitationclinical outcomes

Identifiers

PMID40454770
PMCPMC12128146

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.