Evidence map›Paper›PMID 40454627›Full record

ArticleHuman brain mapping2025

Change in transverse relaxation rates (R

Melissa Lamar, Konstantinos Arfanakis, Ana W Capuano, Shengwei Zhang, Debra A Fleischman, S Duke Han, Victoria N Poole, Sue E Leurgans, David A Bennett, Lisa L Barnes

Abstract read
In one paragraph

Article in Human brain mapping, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Sub-Networks of the Brain RHuman brain mapping · 2026
    Article
  2. Article
  3. Change in transverse relaxation rates (RHuman brain mapping · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Melissa LamarRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.ORCID 0000-0001-6130-5543
Konstantinos ArfanakisRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Ana W CapuanoRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Shengwei ZhangRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Debra A FleischmanRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
S Duke HanRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Victoria N PooleRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Sue E LeurgansRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
David A BennettRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.
Lisa L BarnesRush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, USA.

Funding

SUPPLEMENT TO RUSH ALZHEIMERS DISEASE CENTER COREP30AG010161 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LEURGANS, SUE E. · 1991 to 2020
$49.1M
Rush Alzheimer's Disease Research CenterP30AG072975 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI Lisa L Barnes, Julie A. Schneider · 2021 to 2026
$24.7M
Racial Differences in Late-Life Cognitive Decline and Risk of Alzheimer's DiseaseRF1AG022018 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2016 to 2019
$6.6M
Culturally relevant contributors to cognitive and MRI changes in older LatinosR01AG062711 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI LAMAR, MELISSA · 2020 to 2025
$3.6M
MRI markers of brain aging and risk factors for cognitive decline in older African AmericansR01AG056405 · NIA · RUSH UNIVERSITY MEDICAL CENTER · PI BARNES, LISA L · 2018 to 2023
$3.6M
Multimodal MRI biomarkers of small vessel disease for older persons with and without dementia.UH3NS100599 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2018 to 2020
$3.5M
Racial Differences in Decision Making among Older AdultsR01AG055430 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HAN, DUKE · 2017 to 2021
$3.3M
Longitudinal validation of cerebral small vessel disease biomarkers in diverse community-based older adults without dementiaUF1NS100599 · NINDS · RUSH UNIVERSITY MEDICAL CENTER · PI ARFANAKIS, KONSTANTINOS, SCHNEIDER, JULIE A. · 2021 to 2021
$2.5M
NIA NIH HHS P30 AG010161NIA NIH HHS P30 AG072975NIA NIH HHS P30AG072975NIA NIH HHS R01 AG055430NIA NIH HHS R01 AG056405NIA NIH HHS R01 AG062711NIA NIH HHS RF1 AG022018NINDS NIH HHS UF1 NS100599NINDS NIH HHS UF1NS100599NINDS NIH HHS UH3 NS100599
6 · The paper itself

Abstract

Despite transverse relaxation rate (R

Indexed as

AgingBlack or African AmericanBrainCognitionAgedAged, 80 and overFemaleHumansLongitudinal StudiesMagnetic Resonance ImagingMaleWhite MatterAfrican Americansepisodic memoryglobal cognitionMRIR2

Identifiers

PMID40454627
PMCPMC11683048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.