Evidence map›Paper›PMID 40454545›Full record

SynthesisArtificial organs2025

The Application of Artificial Intelligence and Machine Learning in Left Ventricular Assist Device Implantation: A Systematic Review.

Usama Hussain, Wing Kiu Chou, Abhinav Balasubramanian, Jamolbi Rahmatova, Lydia Wilkinson, Arian Arjomandi Rad, Ioannis Dimarakis, Antonios Kourliouros

Abstract readSystematic Review
In one paragraph

Synthesis in Artificial organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Usama HussainDepartment of Internal Medicine, Royal Berkshire Hospital NHS Foundation Trust, Reading, UK.ORCID https://orcid.org/0009-0004-9198-2114
Wing Kiu ChouDepartment of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford University NHS Foundation Trust, Oxford, UK.
Abhinav BalasubramanianMid and South Essex NHS Foundation Trust, Essex, UK.ORCID https://orcid.org/0000-0001-6051-9929
Jamolbi RahmatovaDepartment of Internal Medicine, United Lincolnshire Hospitals NHS Trust, Lincoln, UK.ORCID https://orcid.org/0000-0002-0329-0918
Lydia WilkinsonDepartment of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford University NHS Foundation Trust, Oxford, UK.
Arian Arjomandi RadDepartment of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford University NHS Foundation Trust, Oxford, UK.ORCID https://orcid.org/0000-0002-4931-4049
Ioannis DimarakisDivision of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington, USA.
Antonios KourliourosDepartment of Cardiothoracic Surgery, Oxford Heart Centre, John Radcliffe Hospital, Oxford University NHS Foundation Trust, Oxford, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis systematic review evaluates the current evidence pertaining to the application of artificial intelligence (AI) and machine learning (ML) in left ventricular assist device (LVAD) implantation. Specifically, the potential of AI/ML in risk stratification, predicting complications, and improving patient outcomes is explored, whereas also identifying key challenges and elucidating avenues of future research.

methodsA comprehensive search was conducted across EMBASE, MEDLINE, Cochrane, PubMed, and Google Scholar databases to identify studies on AI/ML in LVAD implantation up to March 2024. Articles were selected if they utilized AI/ML techniques in LVAD settings and met predefined criteria. A total of 17 studies were included after a rigorous screening and appraisal process.

resultsThe included studies highlighted the use of ML in five main areas: (1) mortality prediction, where ML models demonstrated higher accuracy compared to traditional models; (2) adverse event prediction, including aortic regurgitation and suction events; (3) myocardial recovery, with ML models outperforming traditional stratification methods; (4) deciphering thrombosis risk, with ML identifying key predictors such as younger age and higher BMI; and (5) right ventricular failure prognostication, within which ML models leveraged hemodynamic and imaging data for superior prediction accuracy. Despite such prevalent advances, challenges including data heterogeneity, lack of causality, and limited generalizability persist.

conclusionAI and ML possess transformative potential in optimizing LVAD management, offering both advanced prediction of commonly encountered risk occurrence and personalized care respectively. However, identified issues in AI/ML application, including data interpretability, dataset diversity, and integration into clinical workflows, must be addressed in order to enhance their broader adoption and impact.

Indexed as

Artificial IntelligenceHeart-Assist DevicesHeart FailureMachine LearningHumansRisk Assessmentartificial intelligenceLVADmachine learningmechanical circulatory support

Identifiers

PMID40454545
PMCPMC12760242

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.