Evidence map›Paper›PMID 40454453›Full record

ArticleChemical communications (Cambridge, England)2025

Thioglycoside functionalization

Arun K Thangarasu, Charlie Fehl

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Arun K ThangarasuChemistry Department, Wayne State University, Detroit, MI, 48202, USA. charlie.fehl@wayne.edu.
Charlie FehlChemistry Department, Wayne State University, Detroit, MI, 48202, USA. charlie.fehl@wayne.edu.ORCID http://orcid.org/0000-0001-6182-0879

Funding

Spatiotemporal tools to interrogate O-GlcNAc functions in metabolic signaling and diseaseR35GM142637 · NIGMS · WAYNE STATE UNIVERSITY · PI Charlie Fehl · 2021 to 2026
$2.6M
NIGMS NIH HHS R35 GM142637
6 · The paper itself

Abstract

Thioglycosides are enzymatically stable carbohydrate variants used in biotechnology as probes and investigational drugs. To date, harsh activation conditions limit the scope of thiol-ene sugar ligations. Here, we show that phosphines act as a photoredox mediator to accelerate radical thiol-ene reactions between thiosugars and olefins, enabling mild visible light-driven, ambient, and fully aqueous conditions.

Identifiers

PMID40454453
PMCPMC12128037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.