Evidence map›Paper›PMID 40454385›Full record

ArticleFrontiers in psychiatry2025

Progressive episodes of recurrent syncope due to postural orthostatic tachycardia syndrome truncated by paroxetine: a case report.

Hai Liang, Chen Liang, Lihua Chen, Jiayang Fang, Yongxin Yi, Yidong Gao, Xiang Huang, Xi Chen, Ting Liu, Wei Pan and 1 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hai LiangDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Chen LiangDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Lihua ChenDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Jiayang FangDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Yongxin YiDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Yidong GaoDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Xiang HuangDepartment of Electrophysiology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Xi ChenDepartment of Electrophysiology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Ting LiuDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Wei PanDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Lufeng YinDepartment of Neurology, The Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Postural orthostatic tachycardia syndrome (POTS) is characterized by an increased heart rate upon standing, resulting from abnormal autonomic responses that trigger symptoms when transitioning to an upright position. This syndrome predominantly manifests in late adolescence and early adulthood, with a higher prevalence observed in women. It is commonly triggered by viral infections, pregnancy, surgical procedures, or significant psychological stress. The condition presents with a wide range of symptoms, and the precise etiology of which remains unidentified. A 17-year-old woman with recurrent syncope was admitted to the hospital multiple times. Symptoms resolved rapidly following the initiation of paroxetine, a selective serotonin reuptake inhibitor (SSRI). Preliminary analysis indicated a potential shared pathophysiological basis between POTS and anxiety disorders, with norepinephrine transporter proteins emerging as a significant therapeutic target for both conditions.

Indexed as

anxiety disordersnorepinephrine transporter proteinsparoxetinepostural orthostatic tachycardia syndromerecurrent syncope

Identifiers

PMID40454385
PMCPMC12122513

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