Evidence map›Paper›PMID 40454200›Full record

ArticleBrain communications2025

Significant underascertainment in Huntington's disease.

Sujin Lee, Ben Weisburd, Jiwoo Lee, Kevin Correia, Sophia Zeng, Seri S Park, Jun Wan Shin, Doo Eun Choi, Kyung-Hee Kim, Jae-Hyun Jang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Sujin LeeCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Ben WeisburdCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Jiwoo LeeCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Kevin CorreiaCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Sophia ZengCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Seri S ParkCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Jun Wan ShinCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Doo Eun ChoiCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Kyung-Hee KimCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Jae-Hyun JangCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Tammy GillisCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Heidi L RehmCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
James F GusellaCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Marcy E MacDonaldCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.
Jong-Min LeeCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.ORCID https://orcid.org/0000-0001-5799-0787

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While Huntington's disease (HD), a Mendelian disorder caused by an expanded CAG repeat in

Indexed as

disease prevalenceexponential decay modelfrequency of expanded HTT CAG repeatHuntington’s diseaseunderascertainment

Identifiers

PMID40454200
PMCPMC12123046

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.